| Gene Symbol |
WASF3
|
| Entrez Gene |
10810
|
| Alt Symbol |
Brush-1, SCAR3, WAVE3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
WAS protein family, member 3
|
| Other Description |
WASP family Verprolin-homologous protein 3|protein WAVE-3|verprolin homology domain-containing protein 3|wiskott-Aldrich syndrome protein family member 3
|
| Swissprots |
O94974 Q86VQ2 Q9UPY6
|
| Accessions |
EAX08388 EAX08389 Q9UPY6 AB020707 BAA74923 AB026543 BAA81796 AF134305 AAD33054 AF454702 AAL51032 AK289845 BAF82534 AK294725 BAG57872 AL133590 BC050283 AAH50283 BU736040 S69790 XM_011534889 XP_011533191 XM_011534890 XP_011533192 NM_001291965 NP_001278894 NM_006646 NP_006637
|
| Function |
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. {ECO:0000269|PubMed:17623672, ECO:0000269|PubMed:21834987}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton.
|
| Tissue Specificity |
Expressed in ovary and brain.
|
| Top Pathways |
Adherens junction, Fc gamma R-mediated phagocytosis, Choline metabolism in cancer
|