Gene Symbol |
BPIFB1
|
Entrez Gene |
92747
|
Alt Symbol |
C20orf114, LPLUNC1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
BPI fold containing family B, member 1
|
Other Description |
BPI fold-containing family B member 1|VEMSGP|long palate, lung and nasal epithelium carcinoma associated 1|long palate, lung and nasal epithelium carcinoma-associated protein 1|von Ebner minor salivary gland protein
|
Swissprots |
Q8TDL5 Q5QP43 Q9BQP8 Q6ZRU7 A8K2H8 Q9H4V6 Q6UWY1 Q96HK6 Q9BWZ6
|
Accessions |
EAW76326 Q8TDL5 AF364078 AAM00283 AK127971 BAC87212 AK290243 BAF82932 AK310964 AK313176 BAG35993 AW449208 AY358595 AAQ88958 BC008429 AAH08429 CD696225 HQ448293 ADQ32773 NM_033197 NP_149974
|
Function |
May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS. {ECO:0000269|PubMed:21900486}.
|
Subcellular Location |
Secreted {ECO:0000250}.
|
Tissue Specificity |
Detected in duodenum mucosal crypts of cholera patients, near Paneth cells (at protein level). Detected in trachea, nasal septal epithelium and lung. {ECO:0000269|PubMed:21900486}.
|