Gene Symbol | BPIFB1 |
---|---|
Entrez Gene | 92747 |
Alt Symbol | C20orf114, LPLUNC1 |
Species | Human |
Gene Type | protein-coding |
Description | BPI fold containing family B, member 1 |
Other Description | BPI fold-containing family B member 1|VEMSGP|long palate, lung and nasal epithelium carcinoma associated 1|long palate, lung and nasal epithelium carcinoma-associated protein 1|von Ebner minor salivary gland protein |
Swissprots | Q8TDL5 Q5QP43 Q9BQP8 Q6ZRU7 A8K2H8 Q9H4V6 Q6UWY1 Q96HK6 Q9BWZ6 |
Accessions | EAW76326 Q8TDL5 AF364078 AAM00283 AK127971 BAC87212 AK290243 BAF82932 AK310964 AK313176 BAG35993 AW449208 AY358595 AAQ88958 BC008429 AAH08429 CD696225 HQ448293 ADQ32773 NM_033197 NP_149974 |
Function | May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS. {ECO:0000269|PubMed:21900486}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Detected in duodenum mucosal crypts of cholera patients, near Paneth cells (at protein level). Detected in trachea, nasal septal epithelium and lung. {ECO:0000269|PubMed:21900486}. |