Gene Symbol | B4GALNT3 |
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Entrez Gene | 283358 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | beta-1,4-N-acetyl-galactosaminyl transferase 3 |
Other Description | B4GalNAcT3|Beta4GalNAc-T3|N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase|N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2|NGalNAc-T2|beta-1,4-N-acetylgalactosaminyltransferase 3|beta-1,4-N-acetylgalactosaminyltransferase III|beta4GalNAcT3 |
Swissprots | Q6L9W6 Q8N7T6 Q6ZNC1 |
Accessions | EAW88962 EAW88963 EAW88964 EAW88965 Q6L9W6 AB089940 BAD02449 AK093503 BAC04187 AK097681 BAC05141 AK131277 BAD18454 BC156653 AAI56654 CN400443 NM_173593 NP_775864 |
Function | Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N'- diacetyllactosediamine formation on gastric mucosa. {ECO:0000269|PubMed:16728562}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:16728562}; Single-pass type II membrane protein {ECO:0000269|PubMed:16728562}. Note=Localizes to apical Golgi. |
Tissue Specificity | Highly expressed in testis, colon and stomach. Weakly expressed in other tissues. {ECO:0000269|PubMed:12966086}. |
β-1,4-GalNAc-T3 siRNA (h) - sc-96247 from Santa Cruz Biotechnology
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β-1,4-GalNAc-T3 shRNA Plasmid (h) - sc-96247-SH from Santa Cruz Biotechnology
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β-1,4-GalNAc-T3 shRNA (h) Lentiviral Particles - sc-96247-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU060541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3817 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3817 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03716 from Sigma-Aldrich
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B4GALNT3 siRNA (Human) - CRJ6895 from Cohesion Biosciences
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B4GALNT3 - MBS8235744 from MyBioSource
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shRNA set against Human B4GALNT3 (NM_173593.3) - SHH244374 from Creative biogene
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shRNA set against Human B4GALNT3(NM_173593.3) - SHG089253 from Creative biogene
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Human B4GALNT3 siRNA - orb277396 from Biorbyt
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B4GALNT3 shRNA Plasmid (Human) - CHJ6895 from Cohesion Biosciences
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B4GALNT3 miRNA 3'UTR clone - MiUTR1H-00777 from Creative biogene
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