| Gene Symbol |
TRAK2
|
| Entrez Gene |
66008
|
| Alt Symbol |
ALS2CR3, CALS-C, GRIF-1, GRIF1, MILT2, OIP98
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
trafficking protein, kinesin binding 2
|
| Other Description |
O-linked N-acetylglucosamine transferase interacting protein 98|amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein|gamma-aminobutyric acid(A) receptor-interacting factor|milton homolog 2|trafficking kinesin-binding protein 2
|
| Swissprots |
O60296 Q9C0K6 E7EV21 Q96NS2 Q8WVH7 Q9C0K5
|
| Accessions |
AAX93196 AAY24227 BAB32550 EAW70271 EAW70272 O60296 AB011121 BAA25475 AB038951 BAB32501 AK054763 BAB70803 AK314384 AL832573 CAD89935 BC017999 AAH17999 BC040668 AAH40668 BC041330 AAH41330 BC048093 AAH48093 CA396280 DA314514 DA414989 DA575492 EU832494 ACE87666 EU832575 ACE86977 JF432400 ADZ15617 XM_006712714 XP_006712777 XM_011511690 XP_011509992 XM_011511691 XP_011509993 NM_015049 NP_055864
|
| Function |
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed, with highest expression in heart.
|
| Top Pathways |
GABAergic synapse
|