Gene Symbol | TRAK2 |
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Entrez Gene | 66008 |
Alt Symbol | ALS2CR3, CALS-C, GRIF-1, GRIF1, MILT2, OIP98 |
Species | Human |
Gene Type | protein-coding |
Description | trafficking protein, kinesin binding 2 |
Other Description | O-linked N-acetylglucosamine transferase interacting protein 98|amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein|gamma-aminobutyric acid(A) receptor-interacting factor|milton homolog 2|trafficking kinesin-binding protein 2 |
Swissprots | O60296 Q9C0K6 E7EV21 Q96NS2 Q8WVH7 Q9C0K5 |
Accessions | AAX93196 AAY24227 BAB32550 EAW70271 EAW70272 O60296 AB011121 BAA25475 AB038951 BAB32501 AK054763 BAB70803 AK314384 AL832573 CAD89935 BC017999 AAH17999 BC040668 AAH40668 BC041330 AAH41330 BC048093 AAH48093 CA396280 DA314514 DA414989 DA575492 EU832494 ACE87666 EU832575 ACE86977 JF432400 ADZ15617 XM_006712714 XP_006712777 XM_011511690 XP_011509992 XM_011511691 XP_011509993 NM_015049 NP_055864 |
Function | May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity). {ECO:0000250}. |
Tissue Specificity | Widely expressed, with highest expression in heart. |
Top Pathways | GABAergic synapse |
Human ALS2CR3 peptide - ab23005 from Abcam
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TRAK2 Antibody Blocking Peptide - LS-E25505 from LifeSpan Bioscience
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TRAK2 blocking peptide - GTX89835-PEP from GeneTex
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Goat anti TRAK2 antibody Immunizing peptide - orb16366 from Biorbyt
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ALS2CR3 Peptide - AC21-0333-P from Abcore
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ALS2CR3 Peptide - 45-247P from ProSci
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TRAK2 fusion protein - ag4998 from Proteintech Group
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TRAK2 fusion protein - Ag4753 from Proteintech Group
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Recombinant Human Trafficking kinesin-binding protein 2(TRAK2) ,partial - CSB-YP024220HU CSB-EP024220HU CSB-BP024220HU CSB-MP024220HU from Cusabio
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ALS2CR3/GRIF1, Peptide - MBS425886 from MyBioSource
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ALS2CR3 Protein - NBP1-90182PEP from Novus Biologicals
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TRAK2 Peptide, Human - M34GP16525H from Creative Peptides
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TRAK2 Blocking Peptide - CBP5342 from Cohesion Biosciences
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TRAK2 peptide - orb382199 from Biorbyt
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ALS2CR3 Recombinant Protein Antigen - NBP2-55830PEP from Novus Biologicals
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