RANBP9

Gene Symbol RANBP9
Entrez Gene 10048
Alt Symbol BPM-L, BPM90, RANBPM, RanBP7
Species Human
Gene Type protein-coding
Description RAN binding protein 9
Other Description Ran Binding Protein in the Microtubule organizing center|novel centrosomal protein RanBPM|ran binding protein, centrosomal|ran-binding protein 9|ran-binding protein M
Swissprots A0PJA2 Q7LBR2 Q6P3T7 O94764 Q7Z7F9 Q96S59 B2R8E1
Accessions EAW55341 EAW55342 EAW55343 EAW55344 EAW55345 Q96S59 AB008515 BAA23216 AB055311 BAB62525 AF064606 AAC17111 AF306510 AAK15469 AK313334 BAG36138 BC019886 AAH19886 BC052781 AAH52781 BC053374 BC063849 AAH63849 XM_006714945 XP_006715008 XM_011514205 XP_011512507 NM_005493 NP_005484
Function May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol. Nucleus. Note==Predominantly cytoplasmic. A phosphorylated form is associated with the plasma membrane.
Tissue Specificity Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells. {ECO:0000269|PubMed:12147692, ECO:0000269|PubMed:12361945, ECO:0000269|PubMed:15381419}.

Ran BP-M (A-5) - sc-271726 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ran BP-M (A-5): sc-271726. Western blot analysis of Ran BP-M expression in U-2 OS whole cell lysate.

Ran BP-M (C-16) - sc-46251 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ran BP-M (C-16): sc-46251. Western blot analysis of Ran BP-M expression in mouse testis tissue extract.

Ran BP-M (F-1) - sc-271727 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ran BP-M (F-1): sc-271727. Western blot analysis of Ran BP-M expression in U-2 OS whole cell lysate.

Ran BP-M (H-90) - sc-67050 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ran BP-M (H-90): sc-67050. Western blot analysis of Ran BP-M expression in non-transfected 293T: sc-117752 (A) and human Ran BP-M transfected 293T: sc-117307 (B) whole cell lysates and mouse heart tissue extract (C).

Ran BP-M (K-16) - sc-46254 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Ran BP-M (K-12) - sc-46253 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ran BP-M (K-12): sc-46253. Western blot analysis of Ran BP-M expression in rat heart tissue extract.

Anti-RanBP9 antibody - ab5295 from Abcam

Prices $384.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Ab5295 (3ug/ml) staining of paraffin embedded Human Tonsil. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

Anti-RanBP9 antibody - ab64275 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RanBP9 antibody (ab64275) at 1/2000 dilutionLane 1 : Crude extracts of HeLa cellsLane 2 : Crude extracts of U2OS cells.

Anti-RanBP9 antibody - ab175954 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RanBP9 antibody (ab175954) at 1/1000 dilution + MDA-MB231 cell lysate at 35 µg

Anti-RanBP9 antibody - ab134778 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-RanBP9 antibody (ab134778) at 1/1000 dilution + Mouse brain whole cell extract

Anti-RanBP9 antibody [3C3-E11-C12] - ab150774 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C3-E11-C12
All lanes : Anti-RanBP9 antibody [3C3-E11-C12] (ab150774) at 1/1000 dilutionLane 1 : Jurkat cell lysatesLane 2 : MOLT4 cell lysatesLane 3 : CEM cell lysates

Anti-RanBP9 antibody [EPR9920(B)] - ab140627 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9920(B)
All lanes : Anti-RanBP9 antibody [EPR9920(B)] (ab140627) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Fetal brain tissue lysateLane 3 : JAR cell lysateLysates/proteins at 10 µg per lane.

Anti-RANBPM Antibody - LS-C152811 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RANBPM Antibody - LS-C342051 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-RANBPM Antibody (aa717-729) - LS-C55363 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (3 ug/ml) staining of paraffin embedded human tonsil. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

Anti-RANBPM Antibody (aa339-367) - LS-C162435 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with RANBP9 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

RANBP9 Antibody - NBP2-15087 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RANBP9 Antibody [NBP2-15087] - Sample (30 ug of whole cell lysate) A: Hela B: NT2D1 7. 5% SDS PAGE; antibody diluted at 1:1000.

Importin 9 Polyclonal Antibody - bs-7715R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RANBP9 antibody produced in rabbit - SAB2700327 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RANBP9: <B>Cat. No. SAB2700327</B>: Western Blot analysis of RANBP9 in extracts from <B>Lanes</B><BR/>A. BCL-1 using <B>Cat. No. SAB2700327</B> at a 1:1000 dilution.

Anti-RANBP9 antibody produced in rabbit - HPA050007 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RANBP9: <B>Cat. No. HPA050007</B>: Immunohistochemical staining of human testis shows strong cytoplasmic and nuclear positivity in cells in seminiferus ducts, Leydig cells exhibited strong cytoplasmic staining.

Anti-RANBPM/RANBP9 antibody produced in goat - SAB2500866 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RANBPM / RANBP9: <B>Cat. No. SAB2500866</B>: (3 μg/mL) staining of paraffin embedded human tonsil. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

RANB9 Antibody - middle region (ARP53635_P050) - ARP53635_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RANBP9-Antibody-Center - AP8501c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of RANBP9 Antibody (Center) (Cat. #AP8501c) in MDA-MB231 cell line lysates (35ug/lane). RANBP9 (arrow) was detected using the purified Pab.

RANBPM--RANBP9-Antibody - AF1910a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1910a (3 µg/ml) staining of paraffin embedded human tonsil. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

RANBP9 Antibody - middle region (OAAB05094) - OAAB05094 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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