| Gene Symbol |
Ifng
|
| Entrez Gene |
25712
|
| Alt Symbol |
IFNG2
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
interferon gamma
|
| Other Description |
IFN-gamma
|
| Swissprots |
P01581
|
| Accessions |
AAA41362 CAA26185 CAA26188 EDM16596 P01581 AF010466 AAB66352 NM_138880 NP_620235
|
| Function |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Released primarily from activated T lymphocytes.
|
| Top Pathways |
T cell receptor signaling pathway, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, Measles, Influenza A
|