| Gene Symbol | Ifng |
|---|---|
| Entrez Gene | 25712 |
| Alt Symbol | IFNG2 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | interferon gamma |
| Other Description | IFN-gamma |
| Swissprots | P01581 |
| Accessions | AAA41362 CAA26185 CAA26188 EDM16596 P01581 AF010466 AAB66352 NM_138880 NP_620235 |
| Function | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Released primarily from activated T lymphocytes. |
| Top Pathways | T cell receptor signaling pathway, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, Measles, Influenza A |