Gene Symbol | FHL1 |
---|---|
Entrez Gene | 2273 |
Alt Symbol | FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA |
Species | Human |
Gene Type | protein-coding |
Description | four and a half LIM domains 1 |
Other Description | LIM protein SLIMMER|four and a half LIM domains protein 1|four-and-a-half Lin11, Isl-1 and Mec-3 domains 1|skeletal muscle LIM-protein 1 |
Swissprots | Q13645 O95212 Q9UKZ8 Q9NZ40 Q6IB30 Q5M7Y6 Q5JXI7 Q13230 B7Z5T4 B7Z793 Q9Y630 Q13642 |
Accessions | AAD21579 EAW88476 EAW88477 EAW88478 EAW88479 Q13642 AF063002 AAC72886 AF098518 AAC72390 AF220153 AAF32351 AK091702 BAG52401 AK094024 AK122708 BAG53680 AK223299 BAD97019 AK289411 BAF82100 AK297124 BAH12503 AK299379 BAH13019 AK299381 BAH13020 AK299450 BAH13036 AK300966 BAH13384 AK301642 BAH13529 AK304680 BAH14237 BC010998 AAH10998 BC088369 AAH88369 BE965488 BM995585 CR456974 CAG33255 DA497183 DA917361 DA982372 DC363191 DC373304 DC373386 EU446858 ABZ92387 EU831832 ACE86591 EU832162 ACE87512 EU832256 ACE86826 U29538 AAC35421 U60115 AAC52021 U60118 AAC50795 XM_006724743 XP_006724806 XM_006724744 XP_006724807 XM_006724745 XP_006724808 XM_006724746 XP_006724809 XM_006724747 XP_006724810 XM_011531316 XP_011529618 NM_001159699 NP_001153171 NM_001159700 NP_001153172 NM_001159701 NP_001153173 NM_001159702 NP_001153174 NM_001159703 NP_001153175 NM_001159704 NP_001153176 NM_001167819 NP_001161291 NM_001449 NP_001440 NR_027621 |
Function | May have an involvement in muscle development or hypertrophy. |
Subcellular Location | Isoform 2: Nucleus. Cytoplasm, cytosol. Note=Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes. |
Tissue Specificity | Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle. {ECO:0000269|PubMed:10352231, ECO:0000269|PubMed:10480922, ECO:0000269|PubMed:10524257, ECO:0000269|PubMed:11400158, ECO:0000269|PubMed:9714789}. |
FHL-1 CRISPR/Cas9 KO Plasmid (h) - sc-403541 from Santa Cruz Biotechnology
|
||||||||
FHL-1 HDR Plasmid (h) - sc-403541-HDR from Santa Cruz Biotechnology
|
||||||||
FHL-1 Double Nickase Plasmid (h) - sc-403541-NIC from Santa Cruz Biotechnology
|
||||||||
FHL-1 Double Nickase Plasmid (h2) - sc-403541-NIC-2 from Santa Cruz Biotechnology
|
||||||||
FHL-1 CRISPR Activation Plasmid (h) - sc-403541-ACT from Santa Cruz Biotechnology
|
||||||||
FHL-1 CRISPR Activation Plasmid (h2) - sc-403541-ACT-2 from Santa Cruz Biotechnology
|
||||||||
FHL-1 Lentiviral Activation Particles (h) - sc-403541-LAC from Santa Cruz Biotechnology
|
||||||||
FHL-1 Lentiviral Activation Particles (h2) - sc-403541-LAC-2 from Santa Cruz Biotechnology
|
||||||||
FHL-1 siRNA (h) - sc-37889 from Santa Cruz Biotechnology
|
||||||||
FHL-1 shRNA Plasmid (h) - sc-37889-SH from Santa Cruz Biotechnology
|
||||||||
FHL-1 shRNA (h) Lentiviral Particles - sc-37889-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU073861 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN8682 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8682 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR09108 from Sigma-Aldrich
|
||||||||
FHL1 siRNA (Human) - CRH1590 from Cohesion Biosciences
|
||||||||
FHL1 RNAi - H00002273-R01 from Novus Biologicals
|
||||||||
FHL1 - MBS8230005 from MyBioSource
|
||||||||
FHL-1 CRISPR/Cas9 KO Plasmid (h2) - sc-403541-KO-2 from Santa Cruz Biotechnology
|
||||||||
FHL-1 HDR Plasmid (h2) - sc-403541-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Human FHL1 siRNA - orb262092 from Biorbyt
|
||||||||
FHL1 shRNA Plasmid (Human) - CHH1590 from Cohesion Biosciences
|
||||||||
FHL1 miRNA 3'UTR clone - MiUTR3H-02602 from Creative biogene
|
||||||||
FHL1 miRNA 3'UTR clone - MiUTR3H-02603 from Creative biogene
|
||||||||
FHL1 miRNA 3'UTR clone - MiUTR3H-02604 from Creative biogene
|