FHL1

Gene Symbol FHL1
Entrez Gene 2273
Alt Symbol FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA
Species Human
Gene Type protein-coding
Description four and a half LIM domains 1
Other Description LIM protein SLIMMER|four and a half LIM domains protein 1|four-and-a-half Lin11, Isl-1 and Mec-3 domains 1|skeletal muscle LIM-protein 1
Swissprots Q13645 O95212 Q9UKZ8 Q9NZ40 Q6IB30 Q5M7Y6 Q5JXI7 Q13230 B7Z5T4 B7Z793 Q9Y630 Q13642
Accessions AAD21579 EAW88476 EAW88477 EAW88478 EAW88479 Q13642 AF063002 AAC72886 AF098518 AAC72390 AF220153 AAF32351 AK091702 BAG52401 AK094024 AK122708 BAG53680 AK223299 BAD97019 AK289411 BAF82100 AK297124 BAH12503 AK299379 BAH13019 AK299381 BAH13020 AK299450 BAH13036 AK300966 BAH13384 AK301642 BAH13529 AK304680 BAH14237 BC010998 AAH10998 BC088369 AAH88369 BE965488 BM995585 CR456974 CAG33255 DA497183 DA917361 DA982372 DC363191 DC373304 DC373386 EU446858 ABZ92387 EU831832 ACE86591 EU832162 ACE87512 EU832256 ACE86826 U29538 AAC35421 U60115 AAC52021 U60118 AAC50795 XM_006724743 XP_006724806 XM_006724744 XP_006724807 XM_006724745 XP_006724808 XM_006724746 XP_006724809 XM_006724747 XP_006724810 XM_011531316 XP_011529618 NM_001159699 NP_001153171 NM_001159700 NP_001153172 NM_001159701 NP_001153173 NM_001159702 NP_001153174 NM_001159703 NP_001153175 NM_001159704 NP_001153176 NM_001167819 NP_001161291 NM_001449 NP_001440 NR_027621
Function May have an involvement in muscle development or hypertrophy.
Subcellular Location Isoform 2: Nucleus. Cytoplasm, cytosol. Note=Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes.
Tissue Specificity Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle. {ECO:0000269|PubMed:10352231, ECO:0000269|PubMed:10480922, ECO:0000269|PubMed:10524257, ECO:0000269|PubMed:11400158, ECO:0000269|PubMed:9714789}.

FHL-1 (H-4) - sc-374246 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FHL-1/4 (H-4): sc-374246. Western blot analysis of FHL-1/4 expression in Sol8 whole cell lysate.

FHL-1 (FL-280) - sc-28691 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

FHL-1 (A-17) - sc-13403 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FHL-1 (A-17): sc-13403. Western blot analysis of FHL-1 expression in RAW 264.7 (A), C2C12 (B) and A-10 (C) whole cell lysates and rat skeletal muscle (D) and mouse testis (E) tissue extracts.

FHL-1 (V-16) - sc-23175 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FHL-1 (V-16): sc-23175. Western blot analysis of FHL-1 expression in mouse testis tissue extract.

FHL-1 (F-12) - sc-23176 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FHL-1 (L9-42) - sc-101046 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
FHL-1 (L9-42): sc-101046. Western blot analysis of FHL-1 expression in Raw 264.7 whole cell lysate.

FHL-1 (D-25) - sc-133580 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
FHL-1 (D-25): sc-133580. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.

Anti-FHL1 antibody - ab58067 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
FHL1 antibody (ab58067) at 1ug/lane + Raw cell lysate at 25ug/lane.

Anti-FHL1 antibody - ab26072 from Abcam

Prices $379.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-FHL1 antibody (ab26072) at 0.1 µg/ml

Anti-FHL1 antibody - ab157506 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-FHL1 antibody (ab157506) at 1/1000 dilution + Human fetal muscle lysate

Anti-FHL1 antibody [1D6] - ab119043 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D6
All lanes : Anti-FHL1 antibody [1D6] (ab119043) at 1/1000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY FHL1 cDNALysates/proteins at 5 µg per lane.

Anti-FHL1 antibody [EPR7520] - ab133661 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7520
Anti-FHL1 antibody [EPR7520] (ab133661) at 1/1000 dilution + Human fetal muscle lysate at 10 µgSecondaryHRP labelled Goat anti-Rabbit at 1/2000 dilution

Anti-SLIM / FHL1 Antibody (aa261-272) IHC-plus™ - LS-B2495 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-FHL1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2495 concentration 5 ug/ml.

Anti-SLIM / FHL1 Antibody (clone 2E11) - LS-C172314 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E11
Anti-FHL1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FHL1.

Anti-SLIM / FHL1 Antibody (aa51-100) IHC-plus™ - LS-B3484 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FHL1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3484 concentration 5 ug/ml.

Anti-SLIM / FHL1 Antibody (aa23-121, clone 10C236, Azide-free) - LS-C183622 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10C236

Anti-SLIM / FHL1 Antibody (aa207-256) - LS-C30688 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
FHL1 antibody LS-C30688 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-SLIM / FHL1 Antibody (aa93-166) - LS-C191445 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SLIM / FHL1 Antibody (aa233-246) - LS-C55478 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.01 ug/ml) staining of Human Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SLIM / FHL1 Antibody (aa18-261) - LS-C179177 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLIM / FHL1 Antibody - LS-C311143 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLIM / FHL1 Antibody - LS-C341802 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLIM / FHL1 Antibody (Internal, clone EPR7520) - LS-C154607 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7520
IHC of paraffin-embedded human muscle tissue using anti-FHL1 antibody.

Anti-SLIM / FHL1 Antibody - LS-C346088 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using FHL1 antibody. Blue: DAPI for nuclear staining.

Anti-SLIM / FHL1 Antibody (clone 2E1) - LS-C115289 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E1
Anti-FHL1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FHL1.
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