Gene Symbol | NCOR2 |
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Entrez Gene | 9612 |
Alt Symbol | CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1 |
Species | Human |
Gene Type | protein-coding |
Description | nuclear receptor corepressor 2 |
Other Description | CTG repeat protein 26|T3 receptor-associating factor|silencing mediator for retinoid and thyroid hormone receptors|thyroid-, retinoic-acid-receptor-associated corepressor |
Swissprots | Q56D06 O00613 O15416 Q13354 Q9Y618 Q59GM0 Q9Y5U0 O15421 |
Accessions | EAW98448 EAW98449 EAW98450 EAW98451 EAW98452 EAW98453 Q9Y618 AB209089 BAD92326 AF113003 AAD20946 AF125672 AAD22973 AK127788 AY965853 AAX77219 BC004326 AAH04326 BC020427 BM687540 BU172348 BX390462 CA396349 CN423531 CX873148 L32841 S83390 AAB50847 U80750 AAB91446 X79269 NM_001077261 NP_001070729 NM_001206654 NP_001193583 NM_006312 NP_006303 |
Function | Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival. {ECO:0000269|PubMed:18212045, ECO:0000269|PubMed:23911289}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Ubiquitous. High levels of expression are detected in lung, spleen and brain. |
Top Pathways | Notch signaling pathway, Epstein-Barr virus infection |
Mouse/Human/Rat NCOR2 / SMRT ELISA Kit (DNA-Binding ELISA) - LS-F785 from LifeSpan Bioscience
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NCOR2 Quantification Kit - KA1543 from Novus Biologicals
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Rabbit anti-SMRT Antibody, Affinity Purified - PLA0171 from Sigma-Aldrich
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Nuclear receptor corepressor 2, NCOR2, Human, ELISA Kit - E0334h from ARP American Research Products
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NCOR2 TFact™ DNA-Binding ELISA - TFE-7103 from Assay Biotechnology
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nuclear receptor co-repressor 2, ELISA Kit - MBS9319577 from MyBioSource
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ChIPAb+ SMRT - ChIP Validated Antibody and Primer Set - 17-10057 from EMD Millipore |
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Mouse NCOR2 / SMRT ELISA Kit (Custom ELISA) - LS-F14330 from LifeSpan Bioscience
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Human NCOR2 / SMRT ELISA Kit (Custom ELISA) - LS-F14331 from LifeSpan Bioscience
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Human Nuclear receptor corepressor 2 ELISA Kit - abx253812 from Abbexa
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NCOR2 ELISA Kit - DEIA-XYA1306 from Creative Diagnostics
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Human Nuclear receptor corepressor 2 ELISA Kit - EKE54215 from Biomatik
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NCOR2 - EKH1712 from Nordic BioSite
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Human NCOR2 ELISA Kit - E026975 from Biobool
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Human TRAC ELISA Kit - E037274 from Biobool
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NCOR2 ELISA Kit (Human) (OKEH04298) - OKEH04298 from Aviva Systems Biology
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anti-NCOR2 / SMRT antibody - ARG65814 from Arigo Biolaboratories
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Human Nuclear receptor corepressor 2 (NCOR2) ELISA Kit - AE31542HU from ARP American Research Products
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Nuclear receptor corepressor 2, ELISA Kit - MBS2887347 from MyBioSource
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Mouse NCOR2 / SMRT ELISA Kit (Sandwich ELISA) - LS-F35038 from LifeSpan Bioscience
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Human NCOR2 / SMRT ELISA Kit (Sandwich ELISA) - LS-F35037 from LifeSpan Bioscience
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