| Gene Symbol |
SLC6A15
|
| Entrez Gene |
55117
|
| Alt Symbol |
NTT73, SBAT1, V7-3, hv7-3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 6 (neutral amino acid transporter), member 15
|
| Other Description |
homolog of rat orphan transporter v7-3|orphan sodium- and chloride-dependent neurotransmitter transporter NTT73|orphan transporter v7-3|sodium- and chloride-dependent neurotransmitter transporter NTT73|sodium-coupled branched-chain amino-acid transporter 1|sodium-dependent neutral amino acid transporter B(0)AT2|sodium/chloride dependent neurotransmitter transporter Homo sapiens orphan neurotransmitter transporter NTT7|solute carrier family 6 (neurotransmitter transporter), member 15|solute carrier family 6 member 15|solute carrier family 6, member 15|transporter v7-3
|
| Swissprots |
A8K592 E7ESJ5 B7Z2P7 Q9H2J7 Q9H9F5
|
| Accessions |
EAW97388 EAW97389 EAW97390 Q9H2J7 AF265577 AAG41361 AF351619 AAN76519 AI368909 AK001178 BAA91536 AK022853 BAB14274 AK291207 BAF83896 AK294945 BAH11933 AL050066 BC022253 AAH22253 BC039443 BC045559 BC070040 AAH70040 BE535587 BM696062 CF529868 CR749673 CAH18464 DA247242 XM_011538523 XP_011536825 XM_011538524 XP_011536826 XM_011538525 XP_011536827 NM_001146335 NP_001139807 NM_018057 NP_060527 NM_182767 NP_877499
|
| Function |
Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. {ECO:0000269|PubMed:16226721}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Almost exclusively expressed in the brain. {ECO:0000269|PubMed:16226721}.
|