| Gene Symbol |
TFCP2L1
|
| Entrez Gene |
29842
|
| Alt Symbol |
CRTR1, LBP-9, LBP9
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcription factor CP2-like 1
|
| Other Description |
CP2-related transcriptional repressor 1|CRTR-1|transcription factor CP2-like protein 1|transcription factor LBP-9
|
| Swissprots |
Q9NZI6 Q4ZG43
|
| Accessions |
AAX88871 AAY24072 EAW95250 EAW95251 Q9NZI6 AF198488 AAF32275 AK311692 AL137740 CAI46212 BC020554 BC064698 AAH64698 BM055156 EU446702 ABZ92231 XM_011511024 XP_011509326 XM_011511025 XP_011509327 XM_011511026 XP_011509328 XM_011511027 XP_011509329 NM_014553 NP_055368
|
| Function |
Transcriptional suppressor. May suppress UBP1-mediated transcriptional activation. Required for normal duct development in the salivary gland and kidney (By similarity). Modulates the placental expression of CYP11A1. {ECO:0000250, ECO:0000269|PubMed:10644752}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:10644752}.
|
| Tissue Specificity |
Highly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells. No expression was seen in adrenal NCI-H295A cells or in adrenal tissue. {ECO:0000269|PubMed:10644752}.
|
![Western Blot: TFCP2L1 Overexpression Lysate (Adult Normal) [NBL1-16834] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TFCP2L1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4521_TFCP2L1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16834-img0002.jpg)