Gene Symbol | TFCP2L1 |
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Entrez Gene | 29842 |
Alt Symbol | CRTR1, LBP-9, LBP9 |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor CP2-like 1 |
Other Description | CP2-related transcriptional repressor 1|CRTR-1|transcription factor CP2-like protein 1|transcription factor LBP-9 |
Swissprots | Q9NZI6 Q4ZG43 |
Accessions | AAX88871 AAY24072 EAW95250 EAW95251 Q9NZI6 AF198488 AAF32275 AK311692 AL137740 CAI46212 BC020554 BC064698 AAH64698 BM055156 EU446702 ABZ92231 XM_011511024 XP_011509326 XM_011511025 XP_011509327 XM_011511026 XP_011509328 XM_011511027 XP_011509329 NM_014553 NP_055368 |
Function | Transcriptional suppressor. May suppress UBP1-mediated transcriptional activation. Required for normal duct development in the salivary gland and kidney (By similarity). Modulates the placental expression of CYP11A1. {ECO:0000250, ECO:0000269|PubMed:10644752}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10644752}. |
Tissue Specificity | Highly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells. No expression was seen in adrenal NCI-H295A cells or in adrenal tissue. {ECO:0000269|PubMed:10644752}. |
LBP-9 CRISPR/Cas9 KO Plasmid (h) - sc-404224 from Santa Cruz Biotechnology
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LBP-9 HDR Plasmid (h) - sc-404224-HDR from Santa Cruz Biotechnology
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LBP-9 Double Nickase Plasmid (h) - sc-404224-NIC from Santa Cruz Biotechnology
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LBP-9 Double Nickase Plasmid (h2) - sc-404224-NIC-2 from Santa Cruz Biotechnology
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LBP-9 CRISPR Activation Plasmid (h) - sc-404224-ACT from Santa Cruz Biotechnology
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LBP-9 CRISPR Activation Plasmid (h2) - sc-404224-ACT-2 from Santa Cruz Biotechnology
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LBP-9 Lentiviral Activation Particles (h) - sc-404224-LAC from Santa Cruz Biotechnology
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LBP-9 Lentiviral Activation Particles (h2) - sc-404224-LAC-2 from Santa Cruz Biotechnology
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LBP-9 siRNA (h) - sc-60924 from Santa Cruz Biotechnology
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LBP-9 shRNA Plasmid (h) - sc-60924-SH from Santa Cruz Biotechnology
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LBP-9 shRNA (h) Lentiviral Particles - sc-60924-V from Santa Cruz Biotechnology
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TFCP2L1 RNAi - H00029842-R01 from Novus Biologicals
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MISSION® esiRNA - EHU131231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21253 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21253 from Sigma-Aldrich
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TFCP2L1 siRNA (Human) - CRH9237 from Cohesion Biosciences
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TFCP2L1 - MBS8221868 from MyBioSource
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shRNA set against Human TFCP2L1 (NM_014553.2) - SHH426160 from Creative biogene
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Human TFCP2L1 siRNA - orb269739 from Biorbyt
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TFCP2L1 shRNA Plasmid (Human) - CHH9237 from Cohesion Biosciences
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