Gene Symbol |
MTIF2
|
Entrez Gene |
4528
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
mitochondrial translational initiation factor 2
|
Other Description |
IF-2(Mt)|IF-2mt|IF2(mt)|translation initiation factor IF-2, mitochondrial
|
Swissprots |
D6W5D0 P46199
|
Accessions |
AAM70196 EAX00103 EAX00104 EAX00105 P46199 AF494407 AAM14617 AK225184 AK307993 BC002667 BC009845 BC017243 AAH17243 BC039848 AAH39848 BC054048 AAH54048 BC064977 AAH64977 BC067352 BC082973 BC141420 AAI41421 BC143541 BU684812 CB961193 L34600 AAA67038 XM_005264335 XP_005264392 XM_011532868 XP_011531170 XM_011532869 XP_011531171 XM_011532870 XP_011531172 XM_011532871 XP_011531173 XM_011532872 XP_011531174 XM_011532873 XP_011531175 NM_001005369 NP_001005369 NM_002453 NP_002444
|
Function |
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
|
Subcellular Location |
Mitochondrion.
|
Tissue Specificity |
Expressed in all tissues examined. Highest level in skeletal muscle.
|