Gene Symbol | MTIF2 |
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Entrez Gene | 4528 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial translational initiation factor 2 |
Other Description | IF-2(Mt)|IF-2mt|IF2(mt)|translation initiation factor IF-2, mitochondrial |
Swissprots | D6W5D0 P46199 |
Accessions | AAM70196 EAX00103 EAX00104 EAX00105 P46199 AF494407 AAM14617 AK225184 AK307993 BC002667 BC009845 BC017243 AAH17243 BC039848 AAH39848 BC054048 AAH54048 BC064977 AAH64977 BC067352 BC082973 BC141420 AAI41421 BC143541 BU684812 CB961193 L34600 AAA67038 XM_005264335 XP_005264392 XM_011532868 XP_011531170 XM_011532869 XP_011531171 XM_011532870 XP_011531172 XM_011532871 XP_011531173 XM_011532872 XP_011531174 XM_011532873 XP_011531175 NM_001005369 NP_001005369 NM_002453 NP_002444 |
Function | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. |
Subcellular Location | Mitochondrion. |
Tissue Specificity | Expressed in all tissues examined. Highest level in skeletal muscle. |
IF2 CRISPR/Cas9 KO Plasmid (h) - sc-407402 from Santa Cruz Biotechnology
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IF2 HDR Plasmid (h) - sc-407402-HDR from Santa Cruz Biotechnology
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IF2 Double Nickase Plasmid (h) - sc-407402-NIC from Santa Cruz Biotechnology
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IF2 Double Nickase Plasmid (h2) - sc-407402-NIC-2 from Santa Cruz Biotechnology
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IF2 CRISPR Activation Plasmid (h) - sc-407402-ACT from Santa Cruz Biotechnology
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IF2 CRISPR Activation Plasmid (h2) - sc-407402-ACT-2 from Santa Cruz Biotechnology
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IF2 Lentiviral Activation Particles (h) - sc-407402-LAC from Santa Cruz Biotechnology
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IF2 Lentiviral Activation Particles (h2) - sc-407402-LAC-2 from Santa Cruz Biotechnology
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IF2 siRNA (h) - sc-94300 from Santa Cruz Biotechnology
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IF2 shRNA Plasmid (h) - sc-94300-SH from Santa Cruz Biotechnology
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IF2 shRNA (h) Lentiviral Particles - sc-94300-V from Santa Cruz Biotechnology
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MTIF2 RNAi - H00004528-R02 from Novus Biologicals
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MTIF2 RNAi - H00004528-R01 from Novus Biologicals
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MISSION® esiRNA - EHU039271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14710 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14710 from Sigma-Aldrich
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MTIF2 siRNA (Human) - CRH3003 from Cohesion Biosciences
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shRNA set against Human MTIF2 (NM_002453.2) - SHH346384 from Creative biogene
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shRNA set against Human MTIF2(NM_001005369.1) - SHH206381 from Creative biogene
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Human MTIF2 siRNA - orb263505 from Biorbyt
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MTIF2 shRNA Plasmid (Human) - CHH3003 from Cohesion Biosciences
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MTIF2 miRNA 3'UTR clone - MiUTR1H-06509 from Creative biogene
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MTIF2 miRNA 3'UTR clone - MiUTR4H-TG05710 from Creative biogene
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