| Gene Symbol |
RBM11
|
| Entrez Gene |
54033
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RNA binding motif protein 11
|
| Other Description |
RNA-binding motif protein 11|putative RNA-binding protein 11|splicing regulator RBM11
|
| Swissprots |
Q8NBA1 Q8NFF6 Q6YNC2 P57052
|
| Accessions |
BAA95545 EAX10060 EAX10061 EAX10062 EAX10063 P57052 AF519623 AAM75350 AK091331 BAC03638 AY077695 AAL82535 BC030196 AAH30196 BQ186146 CB153254 XM_005260996 XP_005261053 XM_005260997 XP_005261054 XM_005260998 XP_005261055 XM_006724017 XP_006724080 XM_011529616 XP_011527918 XM_011529617 XP_011527919 XM_011529618 XP_011527920 NM_144770 NP_658983
|
| Function |
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1. {ECO:0000269|PubMed:21984414}.
|
| Subcellular Location |
Nucleus, nucleoplasm {ECO:0000269|PubMed:21984414}. Nucleus speckle {ECO:0000269|PubMed:21984414}. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles.
|
| Tissue Specificity |
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain. {ECO:0000269|PubMed:12036298, ECO:0000269|PubMed:12909339, ECO:0000269|PubMed:21984414}.
|