Gene Symbol | RBM11 |
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Entrez Gene | 54033 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RNA binding motif protein 11 |
Other Description | RNA-binding motif protein 11|putative RNA-binding protein 11|splicing regulator RBM11 |
Swissprots | Q8NBA1 Q8NFF6 Q6YNC2 P57052 |
Accessions | BAA95545 EAX10060 EAX10061 EAX10062 EAX10063 P57052 AF519623 AAM75350 AK091331 BAC03638 AY077695 AAL82535 BC030196 AAH30196 BQ186146 CB153254 XM_005260996 XP_005261053 XM_005260997 XP_005261054 XM_005260998 XP_005261055 XM_006724017 XP_006724080 XM_011529616 XP_011527918 XM_011529617 XP_011527919 XM_011529618 XP_011527920 NM_144770 NP_658983 |
Function | Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1. {ECO:0000269|PubMed:21984414}. |
Subcellular Location | Nucleus, nucleoplasm {ECO:0000269|PubMed:21984414}. Nucleus speckle {ECO:0000269|PubMed:21984414}. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles. |
Tissue Specificity | Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain. {ECO:0000269|PubMed:12036298, ECO:0000269|PubMed:12909339, ECO:0000269|PubMed:21984414}. |
RBM11 CRISPR/Cas9 KO Plasmid (h) - sc-412260 from Santa Cruz Biotechnology
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RBM11 HDR Plasmid (h) - sc-412260-HDR from Santa Cruz Biotechnology
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RBM11 Double Nickase Plasmid (h) - sc-412260-NIC from Santa Cruz Biotechnology
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RBM11 Double Nickase Plasmid (h2) - sc-412260-NIC-2 from Santa Cruz Biotechnology
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RBM11 CRISPR Activation Plasmid (h) - sc-412260-ACT from Santa Cruz Biotechnology
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RBM11 CRISPR Activation Plasmid (h2) - sc-412260-ACT-2 from Santa Cruz Biotechnology
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RBM11 Lentiviral Activation Particles (h) - sc-412260-LAC from Santa Cruz Biotechnology
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RBM11 Lentiviral Activation Particles (h2) - sc-412260-LAC-2 from Santa Cruz Biotechnology
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RBM11 siRNA (h) - sc-91387 from Santa Cruz Biotechnology
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RBM11 shRNA Plasmid (h) - sc-91387-SH from Santa Cruz Biotechnology
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RBM11 shRNA (h) Lentiviral Particles - sc-91387-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU139881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18023 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18023 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12544 from Sigma-Aldrich
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RBM11 siRNA (Human) - CRJ0010 from Cohesion Biosciences
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RBM11 RNAi - H00054033-R01 from Novus Biologicals
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RBM11 - MBS8230208 from MyBioSource
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shRNA set against Human RBM11 (NM_144770.3) - SHH390500 from Creative biogene
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shRNA set against Human RBM11(NM_144770.3) - SHR168340 from Creative biogene
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Human RBM11 siRNA - orb270511 from Biorbyt
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RBM11 shRNA Plasmid (Human) - CHJ0010 from Cohesion Biosciences
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RBM11 miRNA 3'UTR clone - MiUTR3H-15855 from Creative biogene
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