COMT

Gene Symbol	COMT
Entrez Gene	1312
Alt Symbol	HEL-S-98n
Species	Human
Gene Type	protein-coding
Description	catechol-O-methyltransferase
Other Description	catechol O-methyltransferase|epididymis secretory sperm binding protein Li 98n
Swissprots	Q9BWC7 A8MPV9 Q6ICE6 P21964 Q6IB07
Accessions	AAP88929 AEA30239 AEA30240 AEA30241 CAA81263 EAX03010 EAX03011 P21964 AK130031 AK290440 BAF83129 BC000419 AAH00419 BC005867 AAH05867 BC011935 AAH11935 BC100018 AAI00019 BE386545 BE728779 BT007125 AAP35789 BX461394 CR456422 CAG30308 CR456997 CAG33278 CU012983 CAK54414 CU013271 CAK54713 DQ893411 ABM84337 DQ896732 ABM87731 EF103916 EF103917 EF103918 EF103919 EF103920 EF103921 EF103922 EF212883 ABN14343 EF217321 ABN14344 EF217322 ABN14345 FJ224345 ACI46037 FJ410131 ACJ38231 FJ410132 ACJ38232 M58525 AAA68929 M65212 AAA68927 M65213 AAA68928 XM_011529885 XP_011528187 XM_011529886 XP_011528188 XM_011529887 XP_011528189 XM_011529888 XP_011528190 XM_011529889 XP_011528191 XM_011529890 XP_011528192 XM_011529891 XP_011528193 NM_000754 NP_000745 NM_001135161 NP_001128633 NM_001135162 NP_001128634 NM_007310 NP_009294
Function	Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
Subcellular Location	Isoform Soluble: Cytoplasm.
Tissue Specificity	Brain, liver, placenta, lymphocytes and erythrocytes.
Top Pathways	Steroid hormone biosynthesis, Dopaminergic synapse, Tyrosine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

COMT peptide (52-65) - ab45665 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

Human COMT protein fragment - ab117155 from Abcam Category Protein Source E. coli Species Human

COMT Antibody Blocking Peptide - LS-E25808 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COMT Antibody Blocking Peptide - LS-E16284 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COMT Antibody Blocking Peptide - LS-E29492 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

COMT Antibody Blocking Peptide - LS-E29493 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

COMT Antibody Blocking Peptide - LS-E29494 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

COMT Antibody Blocking Peptide - LS-E29495 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

COMT Antibody Blocking Peptide - LS-E26143 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COMT Antibody Blocking Peptide - LS-E29749 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

COMT Antibody Blocking Peptide - LS-E29769 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

COMT Recombinant Protein - H00001312-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human COMT Protein - NBC1-22920 from Novus Biologicals Category Protein Prices $499.00 Sizes 100 µg Species Human

COMT-Antibody-N-term-Blocking-peptide - BP10956a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

COMT (internal) blocking peptide - GTX89277-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

COMT (N Terminus) blocking peptide - GTX89530-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Recombinant Human COMT, CF - 7386-MT-010 from R&D Systems Category Protein Source E. coli-derived, Gly52-Pro271, with an N-terminal Met and a C-terminal 6-His tag

Recombinant human Catechol O-methyltransferase (OPCA00469) - OPCA00469 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

COMT Protein (OPPA02066) - OPPA02066 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human COMT protein - orb90057 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli Species Human

Human COMT protein - orb245144 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

COMT Blocking Peptide - 33R-7005 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

COMT protein - 30R-1264 from Fitzgerald Category Protein Prices $515.00 Sizes 100 µg Source E.coli

COMT Blocking Peptide - abx062453 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

Human COMT Protein - abx065791 from Abbexa Category Protein Source E.coli Species Human

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