Gene Symbol |
RGS18
|
Entrez Gene |
64407
|
Alt Symbol |
RGS13
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
regulator of G-protein signaling 18
|
Other Description |
regulator of G-protein signalling 13|regulator of G-protein signalling 18
|
Swissprots |
Q9NS28 B2RD23
|
Accessions |
CAK32276 EAW91223 Q9NS28 AF076642 AAF80227 AF268036 AAK58589 AK057114 BAG51866 AK292015 BAF84704 AK315377 BAG37770 AV715708 BC020632 AAH20632 DQ891393 ABM82319 DQ894569 ABM85495 XM_011509891 XP_011508193 NM_130782 NP_570138
|
Function |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha- 2, G(i) alpha-3 and G(q) alpha. {ECO:0000269|PubMed:11042171, ECO:0000269|PubMed:11955952}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}.
|
Tissue Specificity |
Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver. {ECO:0000269|PubMed:11042171, ECO:0000269|PubMed:11955952}.
|