Gene Symbol | RGS18 |
---|---|
Entrez Gene | 64407 |
Alt Symbol | RGS13 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 18 |
Other Description | regulator of G-protein signalling 13|regulator of G-protein signalling 18 |
Swissprots | Q9NS28 B2RD23 |
Accessions | CAK32276 EAW91223 Q9NS28 AF076642 AAF80227 AF268036 AAK58589 AK057114 BAG51866 AK292015 BAF84704 AK315377 BAG37770 AV715708 BC020632 AAH20632 DQ891393 ABM82319 DQ894569 ABM85495 XM_011509891 XP_011508193 NM_130782 NP_570138 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha- 2, G(i) alpha-3 and G(q) alpha. {ECO:0000269|PubMed:11042171, ECO:0000269|PubMed:11955952}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver. {ECO:0000269|PubMed:11042171, ECO:0000269|PubMed:11955952}. |