| Gene Symbol | ATP4A |
|---|---|
| Entrez Gene | 495 |
| Alt Symbol | ATP6A |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+/K+ exchanging, alpha polypeptide |
| Other Description | ATPase, H+/K+ transporting, alpha polypeptide|H(+)-K(+)-ATPase alpha subunit|gastric H(+)/K(+) ATPase subunit alpha|gastric H+/K+ ATPase alpha subunit|gastric H,K-ATPase alpha subunit|gastric H,K-ATPase catalytic subunit|gastric hydrogen-potassium ATPase|potassium-transporting ATPase alpha chain 1|proton pump |
| Swissprots | P20648 O00738 |
| Accessions | AAA35577 AAA35988 AAA51010 AAB50172 AAB64182 P20648 AK058032 AK223259 BAD96979 AK308474 AL832971 CAH56338 BC167780 AAI67780 NM_000704 NP_000695 |
| Function | Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Found in gastric mucosa. |
| Top Pathways | Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation |