| Gene Symbol |
ATP4A
|
| Entrez Gene |
495
|
| Alt Symbol |
ATP6A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+/K+ exchanging, alpha polypeptide
|
| Other Description |
ATPase, H+/K+ transporting, alpha polypeptide|H(+)-K(+)-ATPase alpha subunit|gastric H(+)/K(+) ATPase subunit alpha|gastric H+/K+ ATPase alpha subunit|gastric H,K-ATPase alpha subunit|gastric H,K-ATPase catalytic subunit|gastric hydrogen-potassium ATPase|potassium-transporting ATPase alpha chain 1|proton pump
|
| Swissprots |
P20648 O00738
|
| Accessions |
AAA35577 AAA35988 AAA51010 AAB50172 AAB64182 P20648 AK058032 AK223259 BAD96979 AK308474 AL832971 CAH56338 BC167780 AAI67780 NM_000704 NP_000695
|
| Function |
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Found in gastric mucosa.
|
| Top Pathways |
Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation
|
![Western Blot: ATP4A Overexpression Lysate (Adult Normal) [NBL1-07814] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ATP4A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6080_ATP4A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07814-img0002.jpg)