BAK1

Gene Symbol BAK1
Entrez Gene 578
Alt Symbol BAK, BAK-LIKE, BCL2L7, CDN1
Species Human
Gene Type protein-coding
Description BCL2-antagonist/killer 1
Other Description BCL2-like 7 protein|apoptosis regulator BAK|bcl-2 homologous antagonist/killer|bcl-2-like protein 7|bcl2-L-7|pro-apoptotic protein BAK
Swissprots Q16611 C0H5Y7 Q6I9T6 Q92533
Accessions AAO74828 BAA13606 EAX03740 EAX03741 EAX03742 Q16611 AF520590 AAM74949 AK091807 BAG52419 AK292093 BAF84782 AK293547 BAG57025 AK303422 BAG64474 BC004431 AAH04431 BC032789 BC110337 AAI10338 BM855203 CB142221 CR457419 CAG33700 CR627020 CAI46254 DQ892527 ABM83453 DQ895739 ABM86665 U16811 AAA74466 U23765 AAA93066 X84213 CAA58997 XM_011514779 XP_011513081 XM_011514780 XP_011513082 NM_001188 NP_001179
Function In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. {ECO:0000269|PubMed:17157251, ECO:0000269|PubMed:8521816}.
Subcellular Location Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Top Pathways Protein processing in endoplasmic reticulum, Viral carcinogenesis, MicroRNAs in cancer

Bak (D4E4) Rabbit mAb (PE Conjugate) - 14155 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D4E4
Flow cytometric analysis of HeLa cells (blue) and SK-BR-3 cells (green) using Bak (D4E4) Rabbit mAb (PE Conjugate).

Bak (D2D3) Rabbit mAb - 6947 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2D3
Western blot analysis of extracts from various cell lines using Bak (D2D3) Rabbit mAb.

Bak (D4E4) Rabbit mAb - 12105 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4E4
Western blot analysis of extracts from various cell lines using Bak (D4E4) Rabbit mAb.

Bak Antibody - 3814 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from OVCAR8, HT29 and Jurkat cells using Bak Antibody.

Bak Antibody - 3792 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293, A431 and SK-N-MC (human) cells and COS (monkey) cells, using Bak Antibody.

Bak (N-20) - sc-1035 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Bak (N-20): sc-1035. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic staining.

Bak (G-23) - sc-832 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Bak (G-23): sc-832. Western blot analysis of Bak expression in A-431 (A), HeLa (B) and MOLT-4 (C) whole cell lysates.

Bak (H-211) - sc-7873 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Bak (H-211): sc-7873. Western blot analysis of Bak expression in Jurkat whole cell lysate.

Anti-Bak antibody - ab69404 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Bak antibody (ab69404) at 1/1000 dilution + A431 cell lysate

Anti-Bak antibody - ab45008 from Abcam

Prices $370.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-Bak antibody - ab92999 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Bak antibody (ab92999) at 1 µg/ml + A431 (Human epithelial carcinoma cell line) Whole Cell Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Bak antibody - ab2273 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab2273 staining (0.5µg/ml) of A431 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-Bak antibody - ab53153 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bak antibody (ab53153) at 1/500 dilutionLane 1 : extracts from 293 cells, untreatedLane 2 : extracts from 293 cells, treated with the immunizing peptide

Anti-Bak antibody - ab10430 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Bak antibody [AT8B4] - ab104124 from Abcam

Prices $378.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone AT8B4
Anti-Bak antibody [AT8B4] (ab104124) at 1/500 dilution + Mouse lung lyasate at 35 µgSecondaryGoat anti-mouse HRP conjugatedeveloped using the ECL technique

Anti-Bak antibody, prediluted - ab15179 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Human tonsil stained with ab15179.

Anti-Bak antibody [Y164] - ab32371 from Abcam

Prices $403.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y164
Anti-Bak antibody [Y164] (ab32371) at 1/5000 dilution + HeLa cell lysate

Anti-Bak antibody - Aminoterminal end - ab62486 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Bak antibody - Aminoterminal end (ab62486) at 1 µg/mlLane 2 : Anti-Bak antibody - Aminoterminal end (ab62486) at 2 µg/mlLane 1 : L1210 cell lysatesLane 2 : L1210 cell lysatesLysates/proteins at 15 µg per lane.SecondaryAnti rabbit IgG secondary antibody

Anti-Bak antibody - BSA and Azide free - ab77564 from Abcam

Prices $370.00
Sizes 125 µl
Host Rabbit
Clonality Polyclonal

Anti-Bak antibody - N-terminal - ab137646 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bak antibody - N-terminal (ab137646) at 1/1000 dilutionLane 1 : Hela whole cell lysate Lane 2 : HepG2 whole cell lysate Lane 3 : Molt 4 whole cell lysate Lysates/proteins at 30 µg per lane.

Anti-BAK1 / BAK Antibody (aa2-14) - LS-C12099 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-BAK1 / BAK Antibody (N-Terminus) - LS-C12102 from LifeSpan Bioscience

Prices $560.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-BAK1 / BAK Antibody (N-Terminus) - LS-C12108 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BAK1 / BAK Antibody (aa14-36) - LS-C42788 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BAK1 / BAK Antibody - LS-C113058 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
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