| Gene Symbol |
BRAT1
|
| Entrez Gene |
221927
|
| Alt Symbol |
BAAT1, C7orf27, RMFSL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BRCA1-associated ATM activator 1
|
| Other Description |
BRCA1-associated protein required for ATM activation protein 1|HEAT repeat-containing protein C7orf27
|
| Swissprots |
Q6PJG6 Q9UFA3 Q8WVR8 A4D200 Q8IZ43 C9JY24 Q8IW85 Q96IV9 Q9H7J8
|
| Accessions |
EAL23957 EAW87255 EAW87256 EAW87257 EAW87258 EAW87259 EAW87260 Q6PJG6 AI963076 AK024482 BAB15772 AK131083 BAC85133 AK131097 BAC85147 AK311144 AL133088 CAB61405 BC007209 AAH07209 BC015632 AAH15632 BC023561 AAH23561 BC040704 AAH40704 BP363179 XM_005249643 XP_005249700 XM_011515177 XP_011513479 XM_011515178 XP_011513480 XM_011515179 XP_011513481 XM_011515180 XP_011513482 XM_011515181 XP_011513483 XM_011515182 XP_011513484 XM_011515183 XP_011513485 XM_011515184 XP_011513486 XM_011515185 XP_011513487 XM_011515186 XP_011513488 XM_011515187 XP_011513489 NM_152743 NP_689956
|
| Function |
Required for activation of ATM following ionizing radiation. May act by regulating dephosphorylation of ATM. {ECO:0000269|PubMed:16452482}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:16452482}. Note=Present at double strand breaks (DSBs) following ionizing radiation treatment.
|
| Tissue Specificity |
Ubiquitously expressed. {ECO:0000269|PubMed:16452482}.
|