FKRP

Gene Symbol	FKRP
Entrez Gene	79147
Alt Symbol	LGMD2I, MDC1C, MDDGA5, MDDGB5, MDDGC5
Species	Human
Gene Type	protein-coding
Description	fukutin related protein
Other Description	fukutin-related protein
Swissprots	A8K5G7 Q9H9S5
Accessions	CAE90537 EAW57444 EAW57445 Q9H9S5 AJ314847 CAC85633 AK022638 BAB14146 AK095497 BAG53071 AK291282 BAF83971 AW504292 BC002612 AAH02612 BM979509 CX866271 DA123579 DB090073 DN999716 DQ893605 ABM84531 DQ895127 ABM86053 XM_005259247 XP_005259304 XM_005259248 XP_005259305 XM_005259249 XP_005259306 XM_005259250 XP_005259307 XM_011527301 XP_011525603 XM_011527302 XP_011525604 XM_011527303 XP_011525605 XM_011527304 XP_011525606 XM_011527305 XP_011525607 XM_011527306 XP_011525608 XM_011527307 XP_011525609 NM_001039885 NP_001034974 NM_024301 NP_077277
Function	Transferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. {ECO:0000269|PubMed:25279699}.
Subcellular Location	Golgi apparatus membrane {ECO:0000269|PubMed:25279699}; Single-pass type II membrane protein. Secreted. Cell membrane, sarcolemma {ECO:0000250}. Rough endoplasmic reticulum. Note=According to some studies the N- terminal hydrophobic domain is cleaved after translocation to the Golgi apparatus and the protein is secreted. Localization at the cell membrane may require the presence of dystroglycan. At the Golgi apparatus localizes to the middle-to-trans-cisternae, as assessed by MG160 colocalization. Detected in rough endoplasmic reticulum in myocytes. In general, mutants associated with severe clinical phenotypes are retained within the endoplasmic reticulum.
Tissue Specificity	Expressed predominantly in skeletal muscle, placenta, and heart and relatively weakly in brain, lung, liver kidney and pancreas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

FKRP (E-4) - sc-374642 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

FKRP (H-128) - sc-292627 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

FKRP (H-300) - sc-134572 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

FKRP (K-20) - sc-48505 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FKRP (C-16) - sc-48503 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FKRP (N-20) - sc-48506 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-FKRP antibody - ab65243 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FKRP antibody - ab123337 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (C-Terminus, clone 386CT13.1.9, APC) - LS-C221287 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 386CT13.1.9

Anti-FKRP Antibody (C-Terminus, clone 386CT13.1.9, Biotin) - LS-C221289 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 386CT13.1.9

Anti-FKRP Antibody (C-Terminus, clone 386CT13.1.9, AP) - LS-C221290 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 386CT13.1.9

Anti-FKRP Antibody (C-Terminus, clone 386CT13.1.9, Azide-free, HRP) - LS-C221292 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 386CT13.1.9

Anti-FKRP Antibody (C-Terminus, clone 386CT13.1.9, FITC) - LS-C221293 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 386CT13.1.9

Anti-FKRP Antibody (C-Terminus, clone 386CT13.1.9, PE) - LS-C221294 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 386CT13.1.9

Anti-FKRP Antibody (C-Terminus) - LS-C135168 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (aa237-265, AP) - LS-C222558 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (aa237-265, APC) - LS-C222559 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (C-Terminus) - LS-C135169 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (aa1-50) - LS-C119270 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (aa237-265, Biotin) - LS-C222560 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (aa237-265, FITC) - LS-C222561 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (aa237-265, PE) - LS-C222563 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (C-Terminus, clone 386CT13.1.9) - LS-C319149 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 386CT13.1.9

Anti-FKRP Antibody (aa237-265, Azide-free, HRP) - LS-C222562 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKRP Antibody (aa236-265) - LS-C321401 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

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