JAM2

Gene Symbol	JAM2
Entrez Gene	58494
Alt Symbol	C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM
Species	Human
Gene Type	protein-coding
Description	junctional adhesion molecule 2
Other Description	JAM-2|JAM-IT/VE-JAM|junctional adhesion molecule B|vascular endothelial junction-associated molecule
Swissprots	Q6UXG6 Q6YNC1 B4DGT9 B2R6T9 P57087
Accessions	EAX09976 EAX09977 EAX09978 P57087 AF255910 AAF81223 AI742752 AK056079 AK294769 BAG57900 AK312708 BAG35586 AM392801 CAL37679 AM392870 CAL37748 AM393811 CAL38686 AX772824 CAE06261 AY016009 AAG49022 AY077698 AAL82538 AY358361 AAQ88727 BC017779 AAH17779 BG540412 BM804795 BM921497 CX870550 XR_937537 NM_001270408 NP_001257337 NM_021219 NP_067042 NR_072999 NM_001270407 NP_001257336
Function	May play a role in the processes of lymphocyte homing to secondary lymphoid organs.
Subcellular Location	Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Localized at tight junctions of both epithelial and endothelial cells. {ECO:0000250}.
Tissue Specificity	Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells. {ECO:0000269|PubMed:10779521}.
Top Pathways	Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Junctional Adhesion Molecule 2 protein fragment - ab139237 from Abcam Category Protein Source E. coli Species Human

Human Junctional Adhesion Molecule 2 protein fragment - ab192298 from Abcam Category Protein Source HEK 293 cells Species Human

JAM2 Antibody Blocking Peptide - LS-E3072 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

JAM2 Blocking Peptide - LS-E23492 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

JAM2 Antibody Blocking Peptide - LS-E26971 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

JAM2 Antibody Blocking Peptide - LS-E27114 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

JAM-B/VE-JAM Recombinant Protein - H00058494-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human JAM-B/VE-JAM Protein - NBP2-23159 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

JAM-B/VE-JAM Recombinant Protein - H00058494-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

JAM2-Antibody-N-term-Blocking-Peptide - BP14209a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

JAM-B blocking peptide - GTX88482-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

JAM-B blocking peptide - GTX88378-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Recombinant Human JAM-B/VE-JAM Fc Chimera, CF - 1074-VJ-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant human Junctional adhesion molecule B (OPCA00141) - OPCA00141 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Recombinant human Junctional adhesion molecule B (OPCA01261) - OPCA01261 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human JAM-B R protein - orb163347 from Biorbyt Category Protein Prices $255.00, $349.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source Human Cells Species Human

Human JAM2 protein - orb244314 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human JAM-B protein - orb180324 from Biorbyt Category Protein Prices $289.00, $553.00, $2,321.00, $3,281.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human JAM2 protein - orb245892 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Junctional Adhesion Molecule 2 Peptide - AC21-1800-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Junctional Adhesion Molecule 2 Peptide - AC21-1935-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD322 / JAM2 (21-238, His-tag) - AR50698PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CD322 / JAM2 (21-238, His-tag) - AR50698PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CD322 / JAM2 - H00058494-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD322 / JAM2 - H00058494-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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