Gene Symbol | GPR55 |
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Entrez Gene | 9290 |
Alt Symbol | LPIR1 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 55 |
Other Description | G-protein coupled receptor 55 |
Swissprots | Q8N580 Q9Y2T6 |
Accessions | AAD22410 EAW70939 EAW70940 Q9Y2T6 AK292223 BAF84912 BC032694 AAH32694 CR541776 CAG46575 DQ890881 ABM81807 DQ894035 ABM84961 FJ348259 ACI96303 XM_005246952 XP_005247009 XM_011512175 XP_011510477 XM_011512176 XP_011510478 XM_011512177 XP_011510479 NM_005683 NP_005674 |
Function | May be involved in hyperalgesia associated with inflammatory and neuropathic pain (By similarity). Receptor for L- alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function. {ECO:0000250, ECO:0000269|PubMed:19805329}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:18757503}; Multi-pass membrane protein {ECO:0000269|PubMed:18757503}. |
Tissue Specificity | Expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. Expressed in osteoclasts and osteoblasts. {ECO:0000269|PubMed:19805329, ECO:0000269|PubMed:9931487}. |
GPR55 CRISPR/Cas9 KO Plasmid (h) - sc-411265 from Santa Cruz Biotechnology
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GPR55 HDR Plasmid (h) - sc-411265-HDR from Santa Cruz Biotechnology
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GPR55 Double Nickase Plasmid (h) - sc-411265-NIC from Santa Cruz Biotechnology
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GPR55 Double Nickase Plasmid (h2) - sc-411265-NIC-2 from Santa Cruz Biotechnology
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GPR55 CRISPR Activation Plasmid (h) - sc-411265-ACT from Santa Cruz Biotechnology
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GPR55 CRISPR Activation Plasmid (h2) - sc-411265-ACT-2 from Santa Cruz Biotechnology
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GPR55 Lentiviral Activation Particles (h) - sc-411265-LAC from Santa Cruz Biotechnology
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GPR55 Lentiviral Activation Particles (h2) - sc-411265-LAC-2 from Santa Cruz Biotechnology
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GPR55 siRNA (h) - sc-75183 from Santa Cruz Biotechnology
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GPR55 shRNA Plasmid (h) - sc-75183-SH from Santa Cruz Biotechnology
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GPR55 shRNA (h) Lentiviral Particles - sc-75183-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU044061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9607 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9607 from Sigma-Aldrich
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GPR55 siRNA (Human) - CRH6150 from Cohesion Biosciences
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GPR55 - MBS8233231 from MyBioSource
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shRNA set against Human GPR55 (NM_005683.3) - SHH306910 from Creative biogene
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shRNA set against Human GPR55(NM_005683.3) - SHH100343 from Creative biogene
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GPR55 shRNA Plasmid (Human) - CHH6150 from Cohesion Biosciences
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GPR55 miRNA 3'UTR clone - MiUTR1H-04219 from Creative biogene
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