| Gene Symbol |
PHOSPHO1
|
| Entrez Gene |
162466
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatase, orphan 1
|
| Other Description |
phosphoethanolamine/phosphocholine phosphatase
|
| Swissprots |
Q8TCT1 E9PAM0 Q17RU6
|
| Accessions |
CAD33279 CAE84349 CAE84350 EAW94686 Q8TCT1 AJ457189 CAD29803 BC029931 BC117187 AAI17188 BC143884 XM_005257109 XP_005257166 XM_006721731 XP_006721794 XM_006721732 XP_006721795 NM_001143804 NP_001137276 NM_178500 NP_848595
|
| Function |
Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization.
|
| Tissue Specificity |
Expressed at sites of mineralization in bone and cartilage. Highly expressed in osteoblast cell line SaOS-2 which produces a mineralized matrix, but not in MG-63 cell line, which do not mineralize. {ECO:0000269|PubMed:15050893}.
|
| Top Pathways |
Glycerophospholipid metabolism
|