| Gene Symbol |
RENBP
|
| Entrez Gene |
5973
|
| Alt Symbol |
RBP, RNBP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
renin binding protein
|
| Other Description |
AGE|GlcNAc 2-epimerase|N-acetyl-D-glucosamine 2-epimerase|N-acylglucosamine 2-epimerase
|
| Swissprots |
Q96BI6 P51606 B4DNZ3
|
| Accessions |
EAW72771 EAW72772 P51606 AK298125 BAG60405 BC015558 AAH15558 D10232 BAA01082 DQ892270 ABM83196 DQ895471 ABM86397 NM_002910 NP_002901
|
| Function |
Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. {ECO:0000269|PubMed:9990133}.
|
| Top Pathways |
Amino sugar and nucleotide sugar metabolism
|
