Gene Symbol | RENBP |
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Entrez Gene | 5973 |
Alt Symbol | RBP, RNBP |
Species | Human |
Gene Type | protein-coding |
Description | renin binding protein |
Other Description | AGE|GlcNAc 2-epimerase|N-acetyl-D-glucosamine 2-epimerase|N-acylglucosamine 2-epimerase |
Swissprots | Q96BI6 P51606 B4DNZ3 |
Accessions | EAW72771 EAW72772 P51606 AK298125 BAG60405 BC015558 AAH15558 D10232 BAA01082 DQ892270 ABM83196 DQ895471 ABM86397 NM_002910 NP_002901 |
Function | Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. {ECO:0000269|PubMed:9990133}. |
Top Pathways | Amino sugar and nucleotide sugar metabolism |
RENBP CRISPR/Cas9 KO Plasmid (h) - sc-410976 from Santa Cruz Biotechnology
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RENBP HDR Plasmid (h) - sc-410976-HDR from Santa Cruz Biotechnology
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RENBP Double Nickase Plasmid (h) - sc-410976-NIC from Santa Cruz Biotechnology
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RENBP Double Nickase Plasmid (h2) - sc-410976-NIC-2 from Santa Cruz Biotechnology
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RENBP CRISPR Activation Plasmid (h) - sc-410976-ACT from Santa Cruz Biotechnology
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RENBP CRISPR Activation Plasmid (h2) - sc-410976-ACT-2 from Santa Cruz Biotechnology
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RENBP Lentiviral Activation Particles (h) - sc-410976-LAC from Santa Cruz Biotechnology
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RENBP Lentiviral Activation Particles (h2) - sc-410976-LAC-2 from Santa Cruz Biotechnology
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RENBP siRNA (h) - sc-90855 from Santa Cruz Biotechnology
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RENBP shRNA Plasmid (h) - sc-90855-SH from Santa Cruz Biotechnology
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RENBP shRNA (h) Lentiviral Particles - sc-90855-V from Santa Cruz Biotechnology
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RENBP RNAi - H00005973-R01 from Novus Biologicals
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MISSION® esiRNA - EHU159951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18142 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18142 from Sigma-Aldrich
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RENBP siRNA (Human) - CRH4043 from Cohesion Biosciences
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RENBP - MBS8239521 from MyBioSource
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shRNA set against Human RENBP (NM_002910.5) - SHH391912 from Creative biogene
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Human RENBP siRNA - orb264545 from Biorbyt
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RENBP shRNA Plasmid (Human) - CHH4043 from Cohesion Biosciences
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RENBP miRNA 3'UTR clone - MiUTR3H-03013 from Creative biogene
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