Gene Symbol |
HIST1H1A
|
Entrez Gene |
3024
|
Alt Symbol |
H1.1, H1A, H1F1, HIST1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
histone cluster 1, H1a
|
Other Description |
H1 histone family, member 1|histone 1, H1a|histone H1.1|histone H1a
|
Swissprots |
Q02539 Q3MJ34
|
Accessions |
AAN06699 CAA40409 EAW55507 Q02539 BC069492 AAH69492 BC101593 AAI01594 BC112140 AAI12141 EU446958 ABZ92487 NM_005325 NP_005316
|
Function |
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00837, ECO:0000269|PubMed:15911621}. Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837, ECO:0000269|PubMed:15911621}. Note=Mainly localizes in euchromatin.
|