Gene Symbol | HIST1H1A |
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Entrez Gene | 3024 |
Alt Symbol | H1.1, H1A, H1F1, HIST1 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H1a |
Other Description | H1 histone family, member 1|histone 1, H1a|histone H1.1|histone H1a |
Swissprots | Q02539 Q3MJ34 |
Accessions | AAN06699 CAA40409 EAW55507 Q02539 BC069492 AAH69492 BC101593 AAI01594 BC112140 AAI12141 EU446958 ABZ92487 NM_005325 NP_005316 |
Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00837, ECO:0000269|PubMed:15911621}. Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837, ECO:0000269|PubMed:15911621}. Note=Mainly localizes in euchromatin. |
Histone cluster 1 H1A CRISPR/Cas9 KO Plasmid (h) - sc-408028 from Santa Cruz Biotechnology
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Histone cluster 1 H1A HDR Plasmid (h) - sc-408028-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H1A Double Nickase Plasmid (h) - sc-408028-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H1A Double Nickase Plasmid (h2) - sc-408028-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1A CRISPR Activation Plasmid (h) - sc-408028-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H1A CRISPR Activation Plasmid (h2) - sc-408028-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1A Lentiviral Activation Particles (h) - sc-408028-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H1A Lentiviral Activation Particles (h2) - sc-408028-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1A siRNA (h) - sc-105457 from Santa Cruz Biotechnology
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Histone cluster 1 H1A shRNA Plasmid (h) - sc-105457-SH from Santa Cruz Biotechnology
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Histone cluster 1 H1A shRNA (h) Lentiviral Particles - sc-105457-V from Santa Cruz Biotechnology
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Histone H1.1 RNAi - H00003024-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN10050 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10050 from Sigma-Aldrich
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HIST1H1A siRNA (Human) - CRH2055 from Cohesion Biosciences
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HIST1H1A - MBS8235084 from MyBioSource
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shRNA set against Human Hist1h1a (NM_005325.3) - SHH312357 from Creative biogene
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Human HIST1H1A siRNA - orb262557 from Biorbyt
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HIST1H1A shRNA Plasmid (Human) - CHH2055 from Cohesion Biosciences
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HIST1H1A miRNA 3'UTR clone - MiUTR1H-04513 from Creative biogene
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