CANX

Gene Symbol	CANX
Entrez Gene	821
Alt Symbol	CNX, IP90, P90
Species	Human
Gene Type	protein-coding
Description	calnexin
Other Description	major histocompatibility complex class I antigen-binding protein p88
Swissprots	D6R9K3 B4DGP8 B4E2T8 P27824 D3DWQ3 B2R5V8
Accessions	CCD35249 EAW53802 EAW53803 EAW53804 EAW53805 P27824 AF070646 AJ271880 CAB72137 AK129990 BAC85269 AK130080 AK294702 BAG57859 AK304420 BAG65250 AK312334 BAG35255 BC003552 AAH03552 BC042843 AAH42843 BC050534 DQ890627 ABM92244 DQ893794 ABM84720 L10284 AAA36125 L18887 AAA21013 M94859 AAA21749 M98452 AAA35696 S67659 AAB29309 XM_011534664 XP_011532966 XM_011534665 XP_011532967 NM_001024649 NP_001019820 NM_001746 NP_001737
Function	Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. The palmitoylated form preferentially localizes to the perinuclear rough ER.
Top Pathways	Phagosome, Protein processing in endoplasmic reticulum, HTLV-I infection, Thyroid hormone synthesis, Antigen processing and presentation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Calnexin - ER membrane marker full length protein - ab115706 from Abcam Category Protein Prices $339.00, $1,085.00 Sizes 50 µg, 200 µg Source E. coli Species Human

Human Calnexin - ER membrane marker peptide - ab23379 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Calnexin - ER membrane marker protein fragment - ab152012 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human Calnexin - ER membrane marker protein fragment - ab87687 from Abcam Category Protein Prices $188.00, $577.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human Calnexin - ER membrane marker protein fragment - ab117167 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source E. coli Species Human

CANX / Calnexin Antibody Blocking Peptide - LS-E27128 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CANX / Calnexin Antibody Blocking Peptide - LS-E21872 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CANX / Calnexin Antibody Blocking Peptide - LS-E21873 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Calnexin Partial Recombinant Protein - H00000821-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Calnexin Protein - NBP1-30235 from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µg Source E.coli Species Human

Calnexin Recombinant Protein - P3543 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Species Human

Calnexin blocking peptide - GTX88369-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

CANX Protein (OPPA01994) - OPPA01994 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

Human CALNEXIN protein - orb138307 from Biorbyt Category Protein Prices $238.00, $434.00 Sizes 20 μg, 100 μg Source Human Cells Species Human

Calnexin Blocking Peptide - 33R-10926 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

CANX Blocking Peptide - 33R-5505 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CANX Blocking Peptide - 33R-8110 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Calnexin (phospho-Ser583) Blocking Peptide - abx062323 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog

Calnexin Blocking Peptide - abx062324 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog

Calnexin Peptide - AC21-1947-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Calnexin (21-481) - AR09271PU-L from Acris Antibodies Category Protein Prices $585.00 Sizes 500 µg Source E. coli Species Human

Calnexin (21-481) - AR09271PU-N from Acris Antibodies Category Protein Prices $270.00 Sizes 100 µg Source E. coli Species Human

Calnexin - H00000821-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Calnexin - H00000821-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Calnexin - P3543 from Acris Antibodies Category Protein Prices $430.00 Sizes 100 µg Species Human

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