RRM2B

Gene Symbol RRM2B
Entrez Gene 101865579
Alt Symbol -
Species Monkey
Gene Type protein-coding
Description ribonucleotide reductase M2 B (TP53 inducible)
Other Description Ribonucleoside-diphosphate reductase subunit M2 B
Swissprots Q4R741
Accessions EHH64346 Q4R741 AB168988 BAE01083 XM_005563834 XP_005563891
Function Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates from cytoplasm to nucleus in response to DNA damage. {ECO:0000250}.
Top Pathways p53 signaling pathway, Purine metabolism, Glutathione metabolism, Pyrimidine metabolism

Recombinant Macaca fascicularis Ribonucleoside-diphosphate reductase subunit M2 B(RRM2B) - CSB-YP709108MOV CSB-EP709108MOV CSB-BP709108MOV CSB-MP709108MOV from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Monkey

Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B), Recombinant Protein - MBS1472920 from MyBioSource

Category Protein
Prices $1,115.00, $1,115.00, $1,345.00, $1,345.00, $1,765.00, $1,765.00, $2,230.00, $2,230.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Monkey
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