Gene Symbol | LDLR |
---|---|
Entrez Gene | 100009086 |
Alt Symbol | - |
Species | Rabbit |
Gene Type | protein-coding |
Description | low density lipoprotein receptor |
Other Description | LDL receptor|low-density lipoprotein receptor |
Swissprots | P20063 |
Accessions | P20063 JX679211 AFX60885 M11501 AAA31383 NM_001278865 NP_001265794 |
Function | Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endomembrane system; Single-pass type I membrane protein. Membrane, clathrin-coated pit {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus {ECO:0000250}. Early endosome {ECO:0000250}. Late endosome {ECO:0000250}. Cell surface {ECO:0000250}. Lysosome {ECO:0000250}. Note=Found distributed from the plasma membrane to intracellular compartments. Localizes to the Golgi apparatus, early and late endosomes/lysosomes and cell surface in the presence of PCSK9 (By similarity). {ECO:0000250}. |
Top Pathways | Endocytosis, Toxoplasmosis, Hepatitis C, Bile secretion, Ovarian steroidogenesis |
Low density lipoprotein receptor, Rabbit, ELISA Kit - E04L0218 from ARP American Research Products
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Low-density lipoprotein receptor, LDLR, Rabbit, ELISA Kit - E1008Rb from ARP American Research Products
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Rabbit LDLR ELISA Kit - RTL0225 from NeoScientific
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Rabbit LDLR (Low Density Lipoprotein Receptor) ELISA Kit - E-EL-RB2226 from Elabscience
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low density lipoprotein receptor, ELISA Kit - MBS703357 from MyBioSource
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low density lipoprotein receptor, ELISA Kit - MBS9341626 from MyBioSource
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Rabbit Low density lipoprotein receptor ELISA - E04L0218 from BlueGene Biotech
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Rabbit LDLR (Low Density Lipoprotein Receptor) ELISA Kit - E-EL-RB2226 from Iwai North America Inc.
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Rabbit LDLR ELISA Kit - E088306 from Biobool
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Rabbit LDLR ELISA Kit - ERTL0225 from ABclonal
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Rat LDLR ELISA Kit - orb410810 from Biorbyt
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