| Gene Symbol |
NLE1
|
| Entrez Gene |
54475
|
| Alt Symbol |
Nle
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
notchless homolog 1 (Drosophila)
|
| Other Description |
Notchless gene homolog|notchless protein homolog 1
|
| Swissprots |
Q59GJ8 Q9NVX2 Q9BU54 O60868
|
| Accessions |
CBJ05780 CBJ21232 EAW80165 EAW80166 EAW80167 Q9NVX2 AB209111 BAD92348 AJ005257 CAA06444 AK001320 BAA91621 AK303253 BAG64336 AK304508 BAG65315 AW451963 BC002884 AAH02884 BC012075 AAH12075 BE272051 BI752930 BI911995 BP244661 BQ070427 HY320157 XM_011524913 XP_011523215 NM_001014445 NP_001014445 NM_018096 NP_060566
|
| Function |
Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|Ref.5}.
|