NLE1

Gene Symbol	NLE1
Entrez Gene	54475
Alt Symbol	Nle
Species	Human
Gene Type	protein-coding
Description	notchless homolog 1 (Drosophila)
Other Description	Notchless gene homolog|notchless protein homolog 1
Swissprots	Q59GJ8 Q9NVX2 Q9BU54 O60868
Accessions	CBJ05780 CBJ21232 EAW80165 EAW80166 EAW80167 Q9NVX2 AB209111 BAD92348 AJ005257 CAA06444 AK001320 BAA91621 AK303253 BAG64336 AK304508 BAG65315 AW451963 BC002884 AAH02884 BC012075 AAH12075 BE272051 BI752930 BI911995 BP244661 BQ070427 HY320157 XM_011524913 XP_011523215 NM_001014445 NP_001014445 NM_018096 NP_060566
Function	Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|Ref.5}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NLE1 CRISPR/Cas9 KO Plasmid (h) - sc-408646 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NLE1 HDR Plasmid (h) - sc-408646-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NLE1 Double Nickase Plasmid (h) - sc-408646-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NLE1 Double Nickase Plasmid (h2) - sc-408646-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NLE1 CRISPR Activation Plasmid (h) - sc-408646-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NLE1 CRISPR Activation Plasmid (h2) - sc-408646-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NLE1 Lentiviral Activation Particles (h) - sc-408646-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NLE1 Lentiviral Activation Particles (h2) - sc-408646-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NLE1 siRNA (h) - sc-62691 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NLE1 shRNA Plasmid (h) - sc-62691-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NLE1 shRNA (h) Lentiviral Particles - sc-62691-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU072271 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15341 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15341 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08153 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr08153

NLE1 siRNA (Human) - CRJ0082 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human NLE1 (NM_018096.3) - SHH352780 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human NLE1(NM_001014445.1) - SHR012360 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human NLE1(NM_018096.3) - SHR012450 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human NLE1(NM_001014445.1) - SHR012486 from Creative biogene Category siRNA Species Reactivities Human

Human NLE1 siRNA - orb270583 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

NLE1 shRNA Plasmid (Human) - CHJ0082 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

NLE1 miRNA 3'UTR clone - MiUTR1H-06783 from Creative biogene Species Reactivities Human

NLE1 miRNA 3'UTR clone - MiUTR1H-06784 from Creative biogene Species Reactivities Human

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