Gene Symbol |
DHX29
|
Entrez Gene |
54505
|
Alt Symbol |
DDX29
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
Other Description |
ATP-dependent RNA helicase DHX29|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29|DEAH box protein 29|nucleic acid helicase DDXx
|
Swissprots |
Q8IWW2 O75549 Q7Z478 Q9UMH2 Q8N3A1 Q63HN3 Q63HN0
|
Accessions |
EAW54915 EAW54916 EAW54917 EAW54918 Q7Z478 AF070639 AAC25394 AK025145 AK308332 AL079292 CAB45191 AL834496 CAD39154 AY036974 AAK64516 BC035988 BC056219 AAH56219 BX648101 CAH56172 BX648269 CAH56153 BX648688 BX649135 XM_005248544 XP_005248601 XM_006714653 XP_006714716 XM_011543494 XP_011541796 NM_019030 NP_061903
|
Function |
ATP-binding RNA helicase involved in translation initiation. Part of the 43S preinitiation complex that is required for efficient initiation on mammalian mRNAs with structured 5'- UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity. {ECO:0000269|PubMed:19109895, ECO:0000269|PubMed:23706745}.
|
Subcellular Location |
Cytoplasm {ECO:0000305}.
|