Gene Symbol | DHX29 |
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Entrez Gene | 54505 |
Alt Symbol | DDX29 |
Species | Human |
Gene Type | protein-coding |
Description | DEAH (Asp-Glu-Ala-His) box polypeptide 29 |
Other Description | ATP-dependent RNA helicase DHX29|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29|DEAH box protein 29|nucleic acid helicase DDXx |
Swissprots | Q8IWW2 O75549 Q7Z478 Q9UMH2 Q8N3A1 Q63HN3 Q63HN0 |
Accessions | EAW54915 EAW54916 EAW54917 EAW54918 Q7Z478 AF070639 AAC25394 AK025145 AK308332 AL079292 CAB45191 AL834496 CAD39154 AY036974 AAK64516 BC035988 BC056219 AAH56219 BX648101 CAH56172 BX648269 CAH56153 BX648688 BX649135 XM_005248544 XP_005248601 XM_006714653 XP_006714716 XM_011543494 XP_011541796 NM_019030 NP_061903 |
Function | ATP-binding RNA helicase involved in translation initiation. Part of the 43S preinitiation complex that is required for efficient initiation on mammalian mRNAs with structured 5'- UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity. {ECO:0000269|PubMed:19109895, ECO:0000269|PubMed:23706745}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
DDX29 CRISPR/Cas9 KO Plasmid (h) - sc-405089 from Santa Cruz Biotechnology
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DDX29 HDR Plasmid (h) - sc-405089-HDR from Santa Cruz Biotechnology
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DDX29 Double Nickase Plasmid (h) - sc-405089-NIC from Santa Cruz Biotechnology
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DDX29 Double Nickase Plasmid (h2) - sc-405089-NIC-2 from Santa Cruz Biotechnology
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DDX29 CRISPR Activation Plasmid (h) - sc-405089-ACT from Santa Cruz Biotechnology
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DDX29 CRISPR Activation Plasmid (h2) - sc-405089-ACT-2 from Santa Cruz Biotechnology
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DDX29 Lentiviral Activation Particles (h) - sc-405089-LAC from Santa Cruz Biotechnology
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DDX29 Lentiviral Activation Particles (h2) - sc-405089-LAC-2 from Santa Cruz Biotechnology
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DDX29 siRNA (h) - sc-91695 from Santa Cruz Biotechnology
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DDX29 shRNA Plasmid (h) - sc-91695-SH from Santa Cruz Biotechnology
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DDX29 shRNA (h) Lentiviral Particles - sc-91695-V from Santa Cruz Biotechnology
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DHX29 RNAi - H00054505-R01 from Novus Biologicals
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MISSION® esiRNA - EHU000531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7214 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7214 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01545 from Sigma-Aldrich
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DHX29 siRNA (Human) - CRJ0101 from Cohesion Biosciences
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DHX29 - MBS8239059 from MyBioSource
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shRNA set against Human DHX29 (NM_019030.2) - SHH277841 from Creative biogene
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shRNA set against Human DHX29(NM_019030.2) - SHH004511 from Creative biogene
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Human DHX29 siRNA - orb270602 from Biorbyt
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DHX29 shRNA Plasmid (Human) - CHJ0101 from Cohesion Biosciences
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DHX29 miRNA 3'UTR clone - MiUTR1H-02816 from Creative biogene
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