| Gene Symbol |
Hexa
|
| Entrez Gene |
15211
|
| Alt Symbol |
Hex-1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
hexosaminidase A
|
| Other Description |
N-acetyl-beta-glucosaminidase subunit alpha|beta-N-acetylhexosaminidase subunit alpha|beta-hexosaminidase subunit alpha|hexosaminidase subunit A
|
| Swissprots |
P29416 Q64246 Q91XG3
|
| Accessions |
AAA18777 AAC53246 EDL25971 P29416 AK075895 BAC36036 AK075911 BAC36049 AK080777 BAC38018 AK144168 BAE25744 AK150444 BAE29566 AK151960 BAE30831 AK159091 BAE34808 AK159814 BAE35394 AK159890 BAE35457 AK160112 BAE35636 AK167013 BAE39189 AK168186 BAE40146 AK170903 AK179213 AK197174 AK204255 AK211327 AK213356 AK218113 BC010755 AAH10755 U07631 AAA18775 X64331 CAA45615 XR_379397 NM_010421 NP_034551
|
| Function |
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.
|
| Subcellular Location |
Lysosome.
|
| Tissue Specificity |
Ubiquitous. Most abundant in testis, adrenal, epididymis and heart. Low levels seen in the liver. {ECO:0000269|PubMed:7896264}.
|
| Top Pathways |
Lysosome, Amino sugar and nucleotide sugar metabolism, Glycosphingolipid biosynthesis - globo series, Other glycan degradation, Glycosaminoglycan degradation
|
