| Gene Symbol |
HMCES
|
| Entrez Gene |
56941
|
| Alt Symbol |
C3orf37, DC12, SRAPD1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5-hydroxymethylcytosine (hmC) binding, ES cell-specific
|
| Other Description |
ES cell-specific 5hmC-binding protein|SRAP domain-containing protein 1|UPF0361 protein C3orf37|embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein|putative peptidase SRAPD1
|
| Swissprots |
A6NJR9 Q9NRP3 Q96G34 Q96FZ2
|
| Accessions |
EAW79265 EAW79266 Q96FZ2 AF035296 AF201934 AAF86870 AK025883 AK225264 AK297501 BAG59914 AK309891 AY007144 BC009993 AAH09993 BC010125 AAH10125 BC050686 AAH50686 BC088363 AAH88363 BU728549 DQ893084 ABM84010 DQ896351 ABM87350 XM_005247636 XP_005247693 XM_005247637 XP_005247694 XM_011512994 XP_011511296 NM_001006109 NP_001006109 NM_020187 NP_064572
|
| Function |
Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction (PubMed:23945014). {ECO:0000250, ECO:0000269|PubMed:23945014}.
|