Gene Symbol | HMCES |
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Entrez Gene | 56941 |
Alt Symbol | C3orf37, DC12, SRAPD1 |
Species | Human |
Gene Type | protein-coding |
Description | 5-hydroxymethylcytosine (hmC) binding, ES cell-specific |
Other Description | ES cell-specific 5hmC-binding protein|SRAP domain-containing protein 1|UPF0361 protein C3orf37|embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein|putative peptidase SRAPD1 |
Swissprots | A6NJR9 Q9NRP3 Q96G34 Q96FZ2 |
Accessions | EAW79265 EAW79266 Q96FZ2 AF035296 AF201934 AAF86870 AK025883 AK225264 AK297501 BAG59914 AK309891 AY007144 BC009993 AAH09993 BC010125 AAH10125 BC050686 AAH50686 BC088363 AAH88363 BU728549 DQ893084 ABM84010 DQ896351 ABM87350 XM_005247636 XP_005247693 XM_005247637 XP_005247694 XM_011512994 XP_011511296 NM_001006109 NP_001006109 NM_020187 NP_064572 |
Function | Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction (PubMed:23945014). {ECO:0000250, ECO:0000269|PubMed:23945014}. |
C3orf37 CRISPR/Cas9 KO Plasmid (h) - sc-405008 from Santa Cruz Biotechnology
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C3orf37 HDR Plasmid (h) - sc-405008-HDR from Santa Cruz Biotechnology
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C3orf37 Double Nickase Plasmid (h) - sc-405008-NIC from Santa Cruz Biotechnology
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C3orf37 Double Nickase Plasmid (h2) - sc-405008-NIC-2 from Santa Cruz Biotechnology
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C3orf37 CRISPR Activation Plasmid (h) - sc-405008-ACT from Santa Cruz Biotechnology
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C3orf37 CRISPR Activation Plasmid (h2) - sc-405008-ACT-2 from Santa Cruz Biotechnology
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C3orf37 Lentiviral Activation Particles (h) - sc-405008-LAC from Santa Cruz Biotechnology
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C3orf37 Lentiviral Activation Particles (h2) - sc-405008-LAC-2 from Santa Cruz Biotechnology
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C3orf37 siRNA (h) - sc-78041 from Santa Cruz Biotechnology
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C3orf37 shRNA Plasmid (h) - sc-78041-SH from Santa Cruz Biotechnology
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C3orf37 shRNA (h) Lentiviral Particles - sc-78041-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU036741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4896 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4896 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04577 from Sigma-Aldrich
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HMCES siRNA (Human) - CRJ1240 from Cohesion Biosciences
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HMCES - MBS8238695 from MyBioSource
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shRNA set against Human C3orf37 (NM_020187.2) - SHH251665 from Creative biogene
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shRNA set against Human C3orf37(NM_001006109.1) - SHG125089 from Creative biogene
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HMCES shRNA Plasmid (Human) - CHJ1240 from Cohesion Biosciences
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C3ORF37 miRNA 3'UTR clone - MiUTR1H-01391 from Creative biogene
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C3ORF37 miRNA 3'UTR clone - MiUTR3H-14137 from Creative biogene
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