| Gene Symbol |
HTR3D
|
| Entrez Gene |
200909
|
| Alt Symbol |
5HT3D
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
|
| Other Description |
5-hydroxytryptamine (serotonin) receptor 3 family member D|5-hydroxytryptamine receptor 3 subunit D|5-hydroxytryptamine receptor 3D|serotonin 5-HT-3D receptor|serotonin receptor 3D
|
| Swissprots |
J3QT78 Q495N5 Q7Z6B3 Q495N6 C9J2I6 Q70Z44
|
| Accessions |
Q70Z44 AJ437318 CAD24817 AY159812 AAO38166 BC101090 AAI01091 BC101091 AAI01092 BK001746 NM_001145143 NP_001138615 NM_001163646 NP_001157118 NM_182537 NP_872343
|
| Function |
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:17392525}; Multi-pass membrane protein {ECO:0000269|PubMed:17392525}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
|
| Tissue Specificity |
Expressed in liver, as well as fetal and adult colon and kidney. {ECO:0000269|PubMed:12801637}.
|