KRTAP1-3
| Gene Symbol | KRTAP1-3 |
|---|---|
| Entrez Gene | 81850 |
| Alt Symbol | KAP1.2, KAP1.3, KAP1.6, KAP1.8A, KAP1.8B, KAP1.9, KRTAP1.3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | keratin associated protein 1-3 |
| Other Description | keratin associated protein 1.6|keratin-associated protein 1-3|keratin-associated protein 1.8|keratin-associated protein 1.9 |
| Swissprots | Q8IUG1 Q9BYS2 Q8IUG0 Q07628 |
| Accessions | BAC15620 EAW60698 Q8IUG1 AJ406927 CAC27566 BC069161 AAH69161 BC101150 AAI01151 BC101151 AAI01152 BC101152 AAI01153 BC101153 AAI01154 NM_030966 NP_112228 |
| Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
| Tissue Specificity | Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone. {ECO:0000269|PubMed:11279113}. |
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