| Gene Symbol |
DYNLL2
|
| Entrez Gene |
140735
|
| Alt Symbol |
DNCL1B, Dlc2, RSPH22
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dynein, light chain, LC8-type 2
|
| Other Description |
8 kDa dynein light chain b|DLC8b|dynein light chain 2, cytoplasmic|radial spoke 22 homolog
|
| Swissprots |
B2R5B4 Q96FJ2
|
| Accessions |
CAJ42804 EAW94483 EAW94484 Q96FJ2 AF086304 AF112997 AAP97230 AK312125 BAG35061 BC010744 AAH10744 BF528423 CN280282 DA140058 DB022843 NM_080677 NP_542408
|
| Function |
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Top Pathways |
Vasopressin-regulated water reabsorption
|
![Western Blot: Dynein light chain 2 cytoplasmic Overexpression Lysate [NBL1-10071] - Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Dynein light chain 2a cytoplasmic.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8501_Dynein-light-chain-2-cytoplasmic-Overexpression-Lysate-Western-Blot-NBL1-10071-img0003.jpg)