Gene Symbol | DYNLL2 |
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Entrez Gene | 140735 |
Alt Symbol | DNCL1B, Dlc2, RSPH22 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, light chain, LC8-type 2 |
Other Description | 8 kDa dynein light chain b|DLC8b|dynein light chain 2, cytoplasmic|radial spoke 22 homolog |
Swissprots | B2R5B4 Q96FJ2 |
Accessions | CAJ42804 EAW94483 EAW94484 Q96FJ2 AF086304 AF112997 AAP97230 AK312125 BAG35061 BC010744 AAH10744 BF528423 CN280282 DA140058 DB022843 NM_080677 NP_542408 |
Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. |
Top Pathways | Vasopressin-regulated water reabsorption |
DYNLL2 CRISPR/Cas9 KO Plasmid (h) - sc-416984 from Santa Cruz Biotechnology
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DYNLL2 HDR Plasmid (h) - sc-416984-HDR from Santa Cruz Biotechnology
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DYNLL2 Double Nickase Plasmid (h) - sc-416984-NIC from Santa Cruz Biotechnology
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DYNLL2 Double Nickase Plasmid (h2) - sc-416984-NIC-2 from Santa Cruz Biotechnology
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DYNLL2 CRISPR Activation Plasmid (h) - sc-416984-ACT from Santa Cruz Biotechnology
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DYNLL2 CRISPR Activation Plasmid (h2) - sc-416984-ACT-2 from Santa Cruz Biotechnology
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DYNLL2 Lentiviral Activation Particles (h) - sc-416984-LAC from Santa Cruz Biotechnology
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DYNLL2 Lentiviral Activation Particles (h2) - sc-416984-LAC-2 from Santa Cruz Biotechnology
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DYNLL2 siRNA (h) - sc-105316 from Santa Cruz Biotechnology
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DYNLL2 shRNA Plasmid (h) - sc-105316-SH from Santa Cruz Biotechnology
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DYNLL2 shRNA (h) Lentiviral Particles - sc-105316-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU039851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7589 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7589 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00244 from Sigma-Aldrich
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DYNLL2 siRNA (Human) - CRJ5315 from Cohesion Biosciences
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Dynein light chain 2 cytoplasmic RNAi - H00140735-R01 from Novus Biologicals
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DYNLL2 - MBS8213728 from MyBioSource
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shRNA set against Human DYNLL2 (NM_080677.2) - SHH282193 from Creative biogene
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DYNLL2 shRNA Plasmid (Human) - CHJ5315 from Cohesion Biosciences
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DYNLL2 miRNA 3'UTR clone - MiUTR4H-TG02922 from Creative biogene
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