Gene Symbol |
SERPINB10
|
Entrez Gene |
5273
|
Alt Symbol |
PI-10, PI10
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
serpin peptidase inhibitor, clade B (ovalbumin), member 10
|
Other Description |
bomapin|peptidase inhibitor 10|protease inhibitor 10 (ovalbumin type, bomapin)|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10|serpin B10
|
Swissprots |
P48595 Q4VAX7 Q4VAX4
|
Accessions |
EAW63162 P48595 AK314936 BAG37442 BC096217 AAH96217 BC096218 AAH96218 BC096219 AAH96219 BC096220 AAH96220 U35459 AAC50282 XM_011526026 XP_011524328 XM_011526027 XP_011524329 XM_011526028 XP_011524330 NM_005024 NP_005015
|
Function |
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. {ECO:0000269|PubMed:10871600, ECO:0000269|PubMed:7592909}.
|
Subcellular Location |
Nucleus. Cytoplasm. Note=Mostly found in the nucleus.
|
Tissue Specificity |
Expressed specifically in myeloid cells and the bone marrow. {ECO:0000269|PubMed:20433722, ECO:0000269|PubMed:7592909}.
|
Top Pathways |
Amoebiasis
|