Gene Symbol | SERPINB10 |
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Entrez Gene | 5273 |
Alt Symbol | PI-10, PI10 |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
Other Description | bomapin|peptidase inhibitor 10|protease inhibitor 10 (ovalbumin type, bomapin)|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10|serpin B10 |
Swissprots | P48595 Q4VAX7 Q4VAX4 |
Accessions | EAW63162 P48595 AK314936 BAG37442 BC096217 AAH96217 BC096218 AAH96218 BC096219 AAH96219 BC096220 AAH96220 U35459 AAC50282 XM_011526026 XP_011524328 XM_011526027 XP_011524329 XM_011526028 XP_011524330 NM_005024 NP_005015 |
Function | Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. {ECO:0000269|PubMed:10871600, ECO:0000269|PubMed:7592909}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Mostly found in the nucleus. |
Tissue Specificity | Expressed specifically in myeloid cells and the bone marrow. {ECO:0000269|PubMed:20433722, ECO:0000269|PubMed:7592909}. |
Top Pathways | Amoebiasis |
bomapin CRISPR/Cas9 KO Plasmid (h) - sc-408764 from Santa Cruz Biotechnology
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bomapin HDR Plasmid (h) - sc-408764-HDR from Santa Cruz Biotechnology
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bomapin Double Nickase Plasmid (h) - sc-408764-NIC from Santa Cruz Biotechnology
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bomapin Double Nickase Plasmid (h2) - sc-408764-NIC-2 from Santa Cruz Biotechnology
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bomapin CRISPR Activation Plasmid (h) - sc-408764-ACT from Santa Cruz Biotechnology
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bomapin CRISPR Activation Plasmid (h2) - sc-408764-ACT-2 from Santa Cruz Biotechnology
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bomapin Lentiviral Activation Particles (h) - sc-408764-LAC from Santa Cruz Biotechnology
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bomapin Lentiviral Activation Particles (h2) - sc-408764-LAC-2 from Santa Cruz Biotechnology
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bomapin siRNA (h) - sc-106812 from Santa Cruz Biotechnology
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bomapin shRNA Plasmid (h) - sc-106812-SH from Santa Cruz Biotechnology
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bomapin shRNA (h) Lentiviral Particles - sc-106812-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU006421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19138 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19138 from Sigma-Aldrich
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SERPINB10 siRNA (Human) - CRH3522 from Cohesion Biosciences
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SERPINB10 - MBS8214635 from MyBioSource
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shRNA set against Human SERPINB10 (NM_005024.1) - SHH405096 from Creative biogene
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shRNA set against Human SERPINB10(NM_005024.1) - SHR217158 from Creative biogene
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Human SERPINB10 siRNA - orb264024 from Biorbyt
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SERPINB10 shRNA Plasmid (Human) - CHH3522 from Cohesion Biosciences
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SERPINB10 miRNA 3'UTR clone - MiUTR1H-09299 from Creative biogene
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